TY - JOUR
T1 - High-risk African Americans with multiple risk factors for cardiovascular disease
T2 - Challenges in prevention, diagnosis, and treatment
AU - Williams, Richard Allen
AU - Gavin, James R.
AU - Phillips, Robert A.
AU - Sumner, Anne E.
AU - Duncan, Alan K.
AU - Hollar, Danielle
AU - Hennekens, Charles H.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2006
Y1 - 2006
N2 - Coronary heart disease (CHD) is the second leading cause of death in the United States. Despite previous downward trends, which have not persisted, CHD mortality remains higher in African Americans than in Whites. Among African American and White adolescents and adults are trends of increased physical inactivity, smoking, and obesity. Approximately 47 million Americans have metabolic syndrome, a constellation of obesity, hypertension, dyslipidemia, and insulin resistance leading to diabetes. Despite a lower prevalence of metabolic syndrome, African Americans are more insulin resistant than Whites at similar degrees of adiposity, have higher blood pressures, and among women, have more obesity. Since African Americans tend to be diagnosed later and have more risk factors, which confers greater than additive risks, we propose the term "African American multiple-risk patient (AAMRP)." The AAMRP poses clinical and public health challenges for healthcare providers. We provide clinical and public health strategies for early detection and aggressive management of AAMRP.
AB - Coronary heart disease (CHD) is the second leading cause of death in the United States. Despite previous downward trends, which have not persisted, CHD mortality remains higher in African Americans than in Whites. Among African American and White adolescents and adults are trends of increased physical inactivity, smoking, and obesity. Approximately 47 million Americans have metabolic syndrome, a constellation of obesity, hypertension, dyslipidemia, and insulin resistance leading to diabetes. Despite a lower prevalence of metabolic syndrome, African Americans are more insulin resistant than Whites at similar degrees of adiposity, have higher blood pressures, and among women, have more obesity. Since African Americans tend to be diagnosed later and have more risk factors, which confers greater than additive risks, we propose the term "African American multiple-risk patient (AAMRP)." The AAMRP poses clinical and public health challenges for healthcare providers. We provide clinical and public health strategies for early detection and aggressive management of AAMRP.
KW - African Americans
KW - Cardiovascular disease
KW - High-risk
UR - http://www.scopus.com/inward/record.url?scp=33749344490&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33749344490&partnerID=8YFLogxK
M3 - Review article
C2 - 16937598
AN - SCOPUS:33749344490
SN - 1049-510X
VL - 16
SP - 633
EP - 639
JO - Ethnicity and Disease
JF - Ethnicity and Disease
IS - 3
ER -