HIV and cannot see

Claudia M. Prospero Ponce; Nagham Al Zubidi; Hilary A. Beaver; Andrew G. Lee; Derrick A. Huey; Pamela S. Chavis

doi:10.1016/j.survophthal.2013.10.003

HIV and cannot see

Claudia M. Prospero Ponce, Nagham Al Zubidi, Hilary A. Beaver, Andrew G. Lee, Derrick A. Huey, Pamela S. Chavis

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A 55-year-old HIV-positive man presented with acute vision loss in the right eye and altered mental status. Ophthalmic evaluation revealed light perception vision OD with a right relative afferent pupillary defect, conjunctival chemosis, large mutton-fat keratitic precipitates, and diffuse cream-colored vitreous cells. Magnetic resonance imaging of the brain and orbit with and without contrast with fat saturation showed choroidal thickening OD, multifocal deep periventricular and deep ganglionic enhancing lesions, and a suprasellar mass. Brain biopsy showed diffuse large B-cell lymphoma. Intrathecal chemotherapy with methotrexate and cytarabine and whole brain radiation therapy failed. His mental status deteriorated. He developed pancytopenia, neutropenic fever, and septic shock and subsequently expired under palliative care.

Original language	English (US)
Pages (from-to)	468-473
Number of pages	6
Journal	Survey of Ophthalmology
Volume	59
Issue number	4
DOIs	https://doi.org/10.1016/j.survophthal.2013.10.003
State	Published - Jul 2014

Keywords

CNS lymphoma
HAART
HIV
Opportunistic infections
Panophthalmitis
Uveitis

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.survophthal.2013.10.003

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@article{d682918148b54e5caca22b3637f2498c,

title = "HIV and cannot see",

abstract = "A 55-year-old HIV-positive man presented with acute vision loss in the right eye and altered mental status. Ophthalmic evaluation revealed light perception vision OD with a right relative afferent pupillary defect, conjunctival chemosis, large mutton-fat keratitic precipitates, and diffuse cream-colored vitreous cells. Magnetic resonance imaging of the brain and orbit with and without contrast with fat saturation showed choroidal thickening OD, multifocal deep periventricular and deep ganglionic enhancing lesions, and a suprasellar mass. Brain biopsy showed diffuse large B-cell lymphoma. Intrathecal chemotherapy with methotrexate and cytarabine and whole brain radiation therapy failed. His mental status deteriorated. He developed pancytopenia, neutropenic fever, and septic shock and subsequently expired under palliative care.",

keywords = "CNS lymphoma, HAART, HIV, Opportunistic infections, Panophthalmitis, Uveitis",

author = "{Prospero Ponce}, {Claudia M.} and {Al Zubidi}, Nagham and Beaver, {Hilary A.} and Lee, {Andrew G.} and Huey, {Derrick A.} and Chavis, {Pamela S.}",

note = "Funding Information: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, NY .",

year = "2014",

month = jul,

doi = "10.1016/j.survophthal.2013.10.003",

language = "English (US)",

volume = "59",

pages = "468--473",

journal = "Survey of Ophthalmology",

issn = "0039-6257",

publisher = "Elsevier",

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TY - JOUR

T1 - HIV and cannot see

AU - Prospero Ponce, Claudia M.

AU - Al Zubidi, Nagham

AU - Beaver, Hilary A.

AU - Lee, Andrew G.

AU - Huey, Derrick A.

AU - Chavis, Pamela S.

N1 - Funding Information: This work was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York, NY .

PY - 2014/7

Y1 - 2014/7

N2 - A 55-year-old HIV-positive man presented with acute vision loss in the right eye and altered mental status. Ophthalmic evaluation revealed light perception vision OD with a right relative afferent pupillary defect, conjunctival chemosis, large mutton-fat keratitic precipitates, and diffuse cream-colored vitreous cells. Magnetic resonance imaging of the brain and orbit with and without contrast with fat saturation showed choroidal thickening OD, multifocal deep periventricular and deep ganglionic enhancing lesions, and a suprasellar mass. Brain biopsy showed diffuse large B-cell lymphoma. Intrathecal chemotherapy with methotrexate and cytarabine and whole brain radiation therapy failed. His mental status deteriorated. He developed pancytopenia, neutropenic fever, and septic shock and subsequently expired under palliative care.

AB - A 55-year-old HIV-positive man presented with acute vision loss in the right eye and altered mental status. Ophthalmic evaluation revealed light perception vision OD with a right relative afferent pupillary defect, conjunctival chemosis, large mutton-fat keratitic precipitates, and diffuse cream-colored vitreous cells. Magnetic resonance imaging of the brain and orbit with and without contrast with fat saturation showed choroidal thickening OD, multifocal deep periventricular and deep ganglionic enhancing lesions, and a suprasellar mass. Brain biopsy showed diffuse large B-cell lymphoma. Intrathecal chemotherapy with methotrexate and cytarabine and whole brain radiation therapy failed. His mental status deteriorated. He developed pancytopenia, neutropenic fever, and septic shock and subsequently expired under palliative care.

KW - CNS lymphoma

KW - HAART

KW - HIV

KW - Opportunistic infections

KW - Panophthalmitis

KW - Uveitis

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DO - 10.1016/j.survophthal.2013.10.003

M3 - Article

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AN - SCOPUS:84902357127

SN - 0039-6257

VL - 59

SP - 468

EP - 473

JO - Survey of Ophthalmology

JF - Survey of Ophthalmology

IS - 4

ER -

HIV and cannot see

Abstract

Keywords

ASJC Scopus subject areas

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