Horizontal gene transfer among group A streptococci: Implications for pathogenesis and epidemiology

Michael A. Kehoe; Vivek Kapur; Adrian M. Whatmore; James M. Musser

doi:10.1016/0966-842X(96)10058-5

Horizontal gene transfer among group A streptococci: Implications for pathogenesis and epidemiology

Michael A. Kehoe, Vivek Kapur, Adrian M. Whatmore, James M. Musser

Research output: Contribution to journal › Review article › peer-review

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Abstract

Recent studies have revealed that there is considerable genetic diversity among the group A streptococci and that horizontal transfer and recombination of virulence genes have played a major role in generating this diversity. This finding has significant implications for our understanding of the epidemiology and pathogenesis of these common and highly versatile human pathogens.

Original language	English (US)
Pages (from-to)	436-443
Number of pages	8
Journal	Trends in Microbiology
Volume	4
Issue number	11
DOIs	https://doi.org/10.1016/0966-842X(96)10058-5
State	Published - Nov 1996

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

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title = "Horizontal gene transfer among group A streptococci: Implications for pathogenesis and epidemiology",

abstract = "Recent studies have revealed that there is considerable genetic diversity among the group A streptococci and that horizontal transfer and recombination of virulence genes have played a major role in generating this diversity. This finding has significant implications for our understanding of the epidemiology and pathogenesis of these common and highly versatile human pathogens.",

author = "Kehoe, {Michael A.} and Vivek Kapur and Whatmore, {Adrian M.} and Musser, {James M.}",

note = "Funding Information: Work in &authors{\textquoteright} laboratories on grwp A streptococci is suvd bvthe UK &&al Researchc ouncil and The Welkome Trust (MAK.1. bi P&t lieahh !&vices Grant Al-331 19 and an award from the Tex& Advanced Technokgy Program (J.M.M.). J.M.M. is an Established investigator of do American Heart Association.",

year = "1996",

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doi = "10.1016/0966-842X(96)10058-5",

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T2 - Implications for pathogenesis and epidemiology

AU - Kehoe, Michael A.

AU - Kapur, Vivek

AU - Whatmore, Adrian M.

AU - Musser, James M.

N1 - Funding Information: Work in &authors’ laboratories on grwp A streptococci is suvd bvthe UK &&al Researchc ouncil and The Welkome Trust (MAK.1. bi P&t lieahh !&vices Grant Al-331 19 and an award from the Tex& Advanced Technokgy Program (J.M.M.). J.M.M. is an Established investigator of do American Heart Association.

PY - 1996/11

Y1 - 1996/11

N2 - Recent studies have revealed that there is considerable genetic diversity among the group A streptococci and that horizontal transfer and recombination of virulence genes have played a major role in generating this diversity. This finding has significant implications for our understanding of the epidemiology and pathogenesis of these common and highly versatile human pathogens.

AB - Recent studies have revealed that there is considerable genetic diversity among the group A streptococci and that horizontal transfer and recombination of virulence genes have played a major role in generating this diversity. This finding has significant implications for our understanding of the epidemiology and pathogenesis of these common and highly versatile human pathogens.

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Horizontal gene transfer among group A streptococci: Implications for pathogenesis and epidemiology

Abstract

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