Intracranial dual-mode IVUS transducer for image-guided brain therapypreliminary experiments

Carl D. Herickhoff; Patrick D. Wolf; S. W. Smith; Gerald A. Grant; Gavin W. Britz; Christy M. Wilson

doi:10.1109/ULTSYM.2010.5935594

Intracranial dual-mode IVUS transducer for image-guided brain therapypreliminary experiments

Carl D. Herickhoff, Patrick D. Wolf, S. W. Smith, Gerald A. Grant, Gavin W. Britz, Christy M. Wilson

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

In this study, we investigated the feasibility of using 3.5-Fr IVUScatheters for minimally-invasive, image-guided hyperthermia treatment of tumorsin the brain. Feasibility is demonstrated in two ways: 1) by fitting a 3.5-FrIVUS catheter with a 5 × 0.5 × 0.22 mm PZT-4 transducer for 9-MHzimaging, and 2) by testing an identical transducer for therapy potential with3.3-MHz CW excitation. The imaging transducer's performance was compared to a9-Fr, 9-MHz ICE catheter as a gold standard, visualizing a 2.5-cm cyst phantomand a postmortem ovine brain. The therapy transducer was able to maintain apower output of 700 mW, achieving a temperature rise of 19°C at a depth of1.5 mm in excised brain tumor tissue.

Original language	English (US)
Title of host publication	2010 IEEE International Ultrasonics Symposium, IUS 2010
Pages	1502-1505
Number of pages	4
DOIs	https://doi.org/10.1109/ULTSYM.2010.5935594
State	Published - Dec 1 2010
Event	2010 IEEE International Ultrasonics Symposium, IUS 2010 - San Diego, CA, United States Duration: Oct 11 2010 → Oct 14 2010

Other

Other	2010 IEEE International Ultrasonics Symposium, IUS 2010
Country/Territory	United States
City	San Diego, CA
Period	10/11/10 → 10/14/10

Keywords

dual-mode catheter transducer
intravascular ultrasound
ultrasoundhyperthermia

ASJC Scopus subject areas

Acoustics and Ultrasonics

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10.1109/ULTSYM.2010.5935594

Cite this

Herickhoff, CD, Wolf, PD, Smith, SW, Grant, GA, Britz, GW & Wilson, CM 2010, Intracranial dual-mode IVUS transducer for image-guided brain therapypreliminary experiments. in 2010 IEEE International Ultrasonics Symposium, IUS 2010., 5935594, pp. 1502-1505, 2010 IEEE International Ultrasonics Symposium, IUS 2010, San Diego, CA, United States, 10/11/10. https://doi.org/10.1109/ULTSYM.2010.5935594

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abstract = "In this study, we investigated the feasibility of using 3.5-Fr IVUScatheters for minimally-invasive, image-guided hyperthermia treatment of tumorsin the brain. Feasibility is demonstrated in two ways: 1) by fitting a 3.5-FrIVUS catheter with a 5 × 0.5 × 0.22 mm PZT-4 transducer for 9-MHzimaging, and 2) by testing an identical transducer for therapy potential with3.3-MHz CW excitation. The imaging transducer's performance was compared to a9-Fr, 9-MHz ICE catheter as a gold standard, visualizing a 2.5-cm cyst phantomand a postmortem ovine brain. The therapy transducer was able to maintain apower output of 700 mW, achieving a temperature rise of 19°C at a depth of1.5 mm in excised brain tumor tissue.",

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AU - Wolf, Patrick D.

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AU - Wilson, Christy M.

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AB - In this study, we investigated the feasibility of using 3.5-Fr IVUScatheters for minimally-invasive, image-guided hyperthermia treatment of tumorsin the brain. Feasibility is demonstrated in two ways: 1) by fitting a 3.5-FrIVUS catheter with a 5 × 0.5 × 0.22 mm PZT-4 transducer for 9-MHzimaging, and 2) by testing an identical transducer for therapy potential with3.3-MHz CW excitation. The imaging transducer's performance was compared to a9-Fr, 9-MHz ICE catheter as a gold standard, visualizing a 2.5-cm cyst phantomand a postmortem ovine brain. The therapy transducer was able to maintain apower output of 700 mW, achieving a temperature rise of 19°C at a depth of1.5 mm in excised brain tumor tissue.

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Intracranial dual-mode IVUS transducer for image-guided brain therapypreliminary experiments

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