Magnetic resonance imaging of diffuse liver diseases

The intrinsic soft tissue contrast and exquisite sensitivity to contrast agents are unique attributes of magnetic resonance imaging that are beneficial when evaluating diffuse liver disease. Much like a pathologist uses different tissue or cell marker stains, the magnetic resonance imager can use a variety of imaging strategies to elucidate pathologic liver processes in vivo, including processes leading to abnormal lipid metabolization, iron deposition, perfusion abnormalities related to inflammation, fibrosis, vascular occlusion, or infarction and hemorrhage. This article reviews the most important diffuse liver diseases and the corresponding magnetic resonance imaging features.