TY - JOUR
T1 - Mimicking natural bio-mineralization processes
T2 - A new tool for osteochondral scaffold development
AU - Tampieri, Anna
AU - Sprio, Simone
AU - Sandri, Monica
AU - Valentini, Federica
N1 - Funding Information:
The authors gratefully acknowledge the European Commission for financial support under the FP6 contract number NMP4-CT-2006-033277 (TEM-PLANT) and the FP7 contract numbers NMP3-LA-2008-214685 (MAGISTER) and NMP-FP2466373-2 (OPHIS).
PY - 2011/10
Y1 - 2011/10
N2 - In recent years, the concept of regenerative medicine has gained great importance, particularly in the field of orthopaedics, in which current solutions are based mainly on the replacement of damaged tissues with devices that function only as structural replacements with limited regenerative capacity. New regenerative solutions can be obtained by taking inspiration from nature, which surrounds us with a multitude of organisms endowed with extraordinary performance. In particular, bio-mineralization, which is the basis of the formation of load-bearing structures in vertebrate and invertebrate organisms, can be exploited to achieve innovative devices for the repair and reconstruction of bone and osteo-cartilaginous tissues.
AB - In recent years, the concept of regenerative medicine has gained great importance, particularly in the field of orthopaedics, in which current solutions are based mainly on the replacement of damaged tissues with devices that function only as structural replacements with limited regenerative capacity. New regenerative solutions can be obtained by taking inspiration from nature, which surrounds us with a multitude of organisms endowed with extraordinary performance. In particular, bio-mineralization, which is the basis of the formation of load-bearing structures in vertebrate and invertebrate organisms, can be exploited to achieve innovative devices for the repair and reconstruction of bone and osteo-cartilaginous tissues.
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U2 - 10.1016/j.tibtech.2011.04.011
DO - 10.1016/j.tibtech.2011.04.011
M3 - Review article
C2 - 21645938
AN - SCOPUS:80052793845
SN - 0167-7799
VL - 29
SP - 526
EP - 535
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 10
ER -