TY - JOUR
T1 - Molecular mediators of liver ischemia and reperfusion injury
T2 - A brief review
AU - Vardanian, Andrew J.
AU - Busuttil, Ronald W.
AU - Kupiec-Weglinski, Jerzy W.
PY - 2008/5
Y1 - 2008/5
N2 - Ischemia and reperfusion injury is a dynamic process that involves multiple organ systems in various clinical states including transplantation, trauma, and surgery. Research into this field has identified key molecular and signaling players that mediate, modulate, or augment cellular, tissue, and organ injury during this disease process. Further elucidation of the molecular mechanisms should provide the rationale to identify much-needed novel therapeutic options to prevent or ameliorate organ damage due to ischemia and reperfusion in clinics.
AB - Ischemia and reperfusion injury is a dynamic process that involves multiple organ systems in various clinical states including transplantation, trauma, and surgery. Research into this field has identified key molecular and signaling players that mediate, modulate, or augment cellular, tissue, and organ injury during this disease process. Further elucidation of the molecular mechanisms should provide the rationale to identify much-needed novel therapeutic options to prevent or ameliorate organ damage due to ischemia and reperfusion in clinics.
UR - http://www.scopus.com/inward/record.url?scp=44649117021&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44649117021&partnerID=8YFLogxK
U2 - 10.2119/2007-00134.Vardanian
DO - 10.2119/2007-00134.Vardanian
M3 - Short survey
C2 - 18292799
AN - SCOPUS:44649117021
SN - 1076-1551
VL - 14
SP - 337
EP - 345
JO - Molecular Medicine
JF - Molecular Medicine
IS - 5-6
ER -