@inproceedings{e537351d253b41e49a079ed4c2af65a3,
title = "Multiplex in vitro selection of aptamers using nanoporous sol-gel arrays with integrated microheaters",
abstract = "RNA and DNA aptamers that bind to target molecules with high specificity and affinity have been a focus of diagnostics and therapeutic research. These aptamers are obtained by SELEX (Systematic Evolution of Ligands by EXponential enrichment) often requiring more than 10 successive cycles of selection and amplification, where each cycle normally takes 2 days per cycle of SELEX. Here, we have demonstrated the use of sol-gel arrays of proteins in a microfluidic system for efficient selection of RNA aptamers against multiple target molecules.",
keywords = "Aptamer, Microfluidic, SELEX, Sol-gel",
author = "Park, {Seung Min} and Abdullah Ozer and Kylan Szeto and Pangshun Zhu and Raymond Wu and Jiyoung Ahn and Minjoung Jo and Lee, {Dong Ki} and Soyoun Kim and Lis, {John T.} and Moonsoo Jin and Craighead, {Harold G.}",
year = "2009",
language = "English (US)",
isbn = "9780979806421",
series = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "408--411",
booktitle = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
note = "13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 ; Conference date: 01-11-2009 Through 05-11-2009",
}