Nanofluidics for cell and drug delivery

N. Di Trani, A. Grattoni, M. Ferrari

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Management of chronic pathologies requires the development of novel strategies for the delivery of drugs and cell therapies, ad hoc. We have developed implantable micronanofluidic-based platforms that leverage molecular nanoconfinement for the controlled administration of drugs and transplantation of cells. These rely on silicon nanofabricated membranes and 3D-printed polymeric architectures that afford long term function in vivo without complex pumping mechanisms or actuation. In this work, we present our recent advances in zero-order drug delivery implants, remotely tunable delivery devices, and subcutaneous encapsulations for endocrine cells transplantation.

Original languageEnglish (US)
Title of host publication2017 IEEE International Electron Devices Meeting, IEDM 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages40.6.1-40.6.4
ISBN (Electronic)9781538635599
DOIs
StatePublished - Jan 23 2018
Event63rd IEEE International Electron Devices Meeting, IEDM 2017 - San Francisco, United States
Duration: Dec 2 2017Dec 6 2017

Publication series

NameTechnical Digest - International Electron Devices Meeting, IEDM
ISSN (Print)0163-1918

Other

Other63rd IEEE International Electron Devices Meeting, IEDM 2017
Country/TerritoryUnited States
CitySan Francisco
Period12/2/1712/6/17

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

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