TY - JOUR
T1 - Nanomedicine - Challenge and perspectives
AU - Riehemann, Kristina
AU - Schneider, Stefan W.
AU - Luger, Thomas A.
AU - Godin, Biana
AU - Ferrari, Mauro
AU - Fuchs, Harald
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/1/19
Y1 - 2009/1/19
N2 - The application of nanotechnology concepts to medicine joins two large cross-disciplinary fields with an unprecedented societal and economical potential arising from the natural combination of specific achievements in the respective fields. The common basis evolves from the molecular-scale properties relevant to the two fields. Local probes and molecular imaging techniques allow surface and interface properties to be characterized on a nanometer scale at predefined locations, while chemical approaches offer the opportunity to elaborate and address surfaces, for example, for targeted drug delivery, enhanced biocompatibility, and neuroprosthetic purposes. However, concerns arise in this cross-disciplinary area about toxicological aspects and ethical implications. This Review gives an overview of selected recent developments and applications of nanomedicine.
AB - The application of nanotechnology concepts to medicine joins two large cross-disciplinary fields with an unprecedented societal and economical potential arising from the natural combination of specific achievements in the respective fields. The common basis evolves from the molecular-scale properties relevant to the two fields. Local probes and molecular imaging techniques allow surface and interface properties to be characterized on a nanometer scale at predefined locations, while chemical approaches offer the opportunity to elaborate and address surfaces, for example, for targeted drug delivery, enhanced biocompatibility, and neuroprosthetic purposes. However, concerns arise in this cross-disciplinary area about toxicological aspects and ethical implications. This Review gives an overview of selected recent developments and applications of nanomedicine.
KW - Nanoprobes
KW - Nanotechnology
KW - Personalized medicine
KW - Theranostics
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U2 - 10.1002/anie.200802585
DO - 10.1002/anie.200802585
M3 - Review article
C2 - 19142939
AN - SCOPUS:58349119348
SN - 1433-7851
VL - 48
SP - 872
EP - 897
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 5
ER -