TY - JOUR
T1 - Neuroendocrine tumors of genitourinary tract
T2 - Recent advances
AU - Shehabeldin, Ahmed N.
AU - Ro, J. Y.
N1 - Publisher Copyright:
© 2019 The Authors
PY - 2019/10
Y1 - 2019/10
N2 - Primary neuroendocrine tumors of the genitourinary tract are rare and are comprised of a heterogeneous group of neoplasms. These include paraganglioma, well-differentiated neuroendocrine tumors or carcinoid tumors, small-cell neuroendocrine carcinoma, and large-cell neuroendocrine carcinoma. Personal experiences, in addition to the findings of an extensive literature search for pertinent publications, were used to compile the epidemiological data, clinical information, histopathological features, prognostic factors, and therapeutic approaches. We also include molecular alterations and targeted treatments of the various neuroendocrine tumors of the genitourinary tract.
AB - Primary neuroendocrine tumors of the genitourinary tract are rare and are comprised of a heterogeneous group of neoplasms. These include paraganglioma, well-differentiated neuroendocrine tumors or carcinoid tumors, small-cell neuroendocrine carcinoma, and large-cell neuroendocrine carcinoma. Personal experiences, in addition to the findings of an extensive literature search for pertinent publications, were used to compile the epidemiological data, clinical information, histopathological features, prognostic factors, and therapeutic approaches. We also include molecular alterations and targeted treatments of the various neuroendocrine tumors of the genitourinary tract.
KW - Carcinoid tumor
KW - Genitourinary neuroendocrine carcinoma
KW - Genitourinary neuroendocrine tumor
KW - Large-cell neuroendocrine carcinoma
KW - Small-cell carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85068753835&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068753835&partnerID=8YFLogxK
U2 - 10.1016/j.anndiagpath.2019.06.009
DO - 10.1016/j.anndiagpath.2019.06.009
M3 - Review article
C2 - 31306859
AN - SCOPUS:85068753835
SN - 1092-9134
VL - 42
SP - 48
EP - 58
JO - Annals of Diagnostic Pathology
JF - Annals of Diagnostic Pathology
ER -