TY - JOUR
T1 - Noninvasive Brain Stimulation Techniques for Treatment-Resistant Depression
T2 - Transcranial Magnetic Stimulation and Transcranial Direct Current Stimulation
AU - Boscutti, Andrea
AU - Juliana Mendonca De Figueiredo, Mendonca De Figueiredo
AU - Dana Razouq, Razouq
AU - Murphy, Nicholas
AU - Cho, Raymond
AU - Selvaraj, Sudhakar
N1 - Funding Information:
Funding: S. Selvaraj has received grants/research support from NIMH, United States (1R21MH119441-01A1), NIMH (1R21MH129888-01A1), NICHD 1R21HD106779-01A1, and Anne and Don Fizer Foundation, United States. N. Murphy has received grants/research support from NIMH (1R21MH119441-01A1); REAM Misophonia Research Fund (The REAM Foundation - YR01); Caroline Wiess Law Fund for Research in Molecular Medicine. Role of Funder: The content of this study is solely the responsibility of the authors and does not necessarily represent the official views of the NIH, NIMH, and NICHD. The UT Health institution played no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the article; and decision to submit the article for publication.
Funding Information:
Funding: S. Selvaraj has received grants/research support from NIMH, United States ( 1R21MH119441-01A1 ), NIMH ( 1R21MH129888-01A1 ), NICHD 1R21HD106779-01A1 , and Anne and Don Fizer Foundation, United States. N. Murphy has received grants/research support from NIMH (1R21MH119441-01A1); REAM Misophonia Research Fund (The REAM Foundation - YR01); Caroline Wiess Law Fund for Research in Molecular Medicine . Role of Funder: The content of this study is solely the responsibility of the authors and does not necessarily represent the official views of the NIH, NIMH, and NICHD. The UT Health institution played no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the article; and decision to submit the article for publication.
PY - 2023/6
Y1 - 2023/6
N2 - Transcranial magnetic stimulation is a safe, effective, and well-tolerated intervention for depression; it is currently approved for treatment-resistant depression. This article summarizes the mechanism of action, evidence of clinical efficacy, and the clinical aspects of this intervention, including patient evaluation, stimulation parameters selection, and safety considerations. Transcranial direct current stimulation is another neuromodulation treatment for depression; although promising, the technique is not currently approved for clinical use in the United States. The final section outlines the open challenges and future directions of the field.
AB - Transcranial magnetic stimulation is a safe, effective, and well-tolerated intervention for depression; it is currently approved for treatment-resistant depression. This article summarizes the mechanism of action, evidence of clinical efficacy, and the clinical aspects of this intervention, including patient evaluation, stimulation parameters selection, and safety considerations. Transcranial direct current stimulation is another neuromodulation treatment for depression; although promising, the technique is not currently approved for clinical use in the United States. The final section outlines the open challenges and future directions of the field.
KW - Neuromodulation
KW - Neuroplasticity
KW - Noninvasive brain stimulation
KW - TMS
KW - Transcranial direct current stimulation
KW - Transcranial magnetic stimulation
KW - Treatment-resistant depression
KW - tDCS
KW - Transcranial Direct Current Stimulation/methods
KW - Humans
KW - Brain/physiology
KW - Depression
KW - Treatment Outcome
KW - Transcranial Magnetic Stimulation/methods
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UR - http://www.scopus.com/inward/citedby.url?scp=85150285504&partnerID=8YFLogxK
U2 - 10.1016/j.psc.2023.02.005
DO - 10.1016/j.psc.2023.02.005
M3 - Review article
C2 - 37149347
AN - SCOPUS:85150285504
SN - 0193-953X
VL - 46
SP - 307
EP - 329
JO - Psychiatric Clinics of North America
JF - Psychiatric Clinics of North America
IS - 2
ER -