NR4A subfamily

Weidong Le; Jie Dong; Sheng Chen

doi:10.1016/B978-0-12-809324-5.00710-0

NR4A subfamily

Weidong Le, Jie Dong, Sheng Chen

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The NR4A subfamily includes three members, Nur77, Nurr1, and NOR-1, which belong to orphan nuclear receptor superfamily. These factors play essential roles in cell proliferation, growth, differentiation, and apoptosis. Furthermore, dysregulation of these factors has been implicated in several human diseases, such as Parkinson’s disease, immunological diseases, vascular disease and tumor. In this article, we will review the structure and functions of these factors as well as their relationship with diseases.

Original language	English (US)
Title of host publication	The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier Science Ltd.
Pages	311-315
Number of pages	5
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.00710-0
State	Published - Jan 1 2016

Keywords

Dopamine
NOR-1
Nur77
Nurr1
Parkinson’s disease

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-809324-5.00710-0

Cite this

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title = "NR4A subfamily",

abstract = "The NR4A subfamily includes three members, Nur77, Nurr1, and NOR-1, which belong to orphan nuclear receptor superfamily. These factors play essential roles in cell proliferation, growth, differentiation, and apoptosis. Furthermore, dysregulation of these factors has been implicated in several human diseases, such as Parkinson{\textquoteright}s disease, immunological diseases, vascular disease and tumor. In this article, we will review the structure and functions of these factors as well as their relationship with diseases.",

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author = "Weidong Le and Jie Dong and Sheng Chen",

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doi = "10.1016/B978-0-12-809324-5.00710-0",

language = "English (US)",

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AU - Le, Weidong

AU - Dong, Jie

AU - Chen, Sheng

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The NR4A subfamily includes three members, Nur77, Nurr1, and NOR-1, which belong to orphan nuclear receptor superfamily. These factors play essential roles in cell proliferation, growth, differentiation, and apoptosis. Furthermore, dysregulation of these factors has been implicated in several human diseases, such as Parkinson’s disease, immunological diseases, vascular disease and tumor. In this article, we will review the structure and functions of these factors as well as their relationship with diseases.

AB - The NR4A subfamily includes three members, Nur77, Nurr1, and NOR-1, which belong to orphan nuclear receptor superfamily. These factors play essential roles in cell proliferation, growth, differentiation, and apoptosis. Furthermore, dysregulation of these factors has been implicated in several human diseases, such as Parkinson’s disease, immunological diseases, vascular disease and tumor. In this article, we will review the structure and functions of these factors as well as their relationship with diseases.

KW - Dopamine

KW - NOR-1

KW - Nur77

KW - Nurr1

KW - Parkinson’s disease

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DO - 10.1016/B978-0-12-809324-5.00710-0

M3 - Chapter

SP - 311

EP - 315

BT - The Curated Reference Collection in Neuroscience and Biobehavioral Psychology

PB - Elsevier Science Ltd.

ER -

NR4A subfamily

Abstract

Keywords

ASJC Scopus subject areas

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