P-Bodies React to Stress and Nonsense

Ivone Bruno; Miles F. Wilkinson

doi:10.1016/j.cell.2006.06.003

P-Bodies React to Stress and Nonsense

Ivone Bruno, Miles F. Wilkinson

Academic Institute

Research output: Contribution to journal › Short survey › peer-review

33 Scopus citations

Abstract

P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.

Original language	English (US)
Pages (from-to)	1036-1038
Number of pages	3
Journal	Cell
Volume	125
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2006.06.003
State	Published - Jun 2006

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2006.06.003

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abstract = "P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of {"}mRNA purgatory.{"} Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.",

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AB - P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs are targeted to P-bodies to undergo rapid decay.

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P-Bodies React to Stress and Nonsense

Abstract

ASJC Scopus subject areas

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