TY - JOUR
T1 - Parathyroid scintigraphy in renal hyperparathyroidism
T2 - The added diagnostic value of SPECT and SPECT/CT
AU - Taïeb, David
AU - Ureña-Torres, Pablo
AU - Zanotti-Fregonara, Paolo
AU - Rubello, Domenico
AU - Ferretti, Alice
AU - Henter, Ioline
AU - Henry, Jean François
AU - Schiavi, Francesca
AU - Opocher, Giuseppe
AU - Blickman, Johan G.
AU - Colletti, Patrick M.
AU - Hindié, Elif
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2013/8
Y1 - 2013/8
N2 - Secondary hyperparathyroidism (sHPT) is a major complication for patients with end-stage renal disease on long-term hemodialysis or peritoneal dialysis. When the disease is resistant to medical treatment, patients with severe sHPT are typically referred for parathyroidectomy (PTx), which usually improves biological parameters as well as clinical signs and symptoms. Unfortunately, early surgical failure with persistent disease may occur in 5%-10% of patients and recurrence reaches 20%-30% at 5 years. Presently, the use of parathyroid scintigraphy in sHPT is usually limited to the management of surgical failures after initial PTx. This review describes the strengths and limitations of typical 99mTc-sestamibi imaging protocols, and highlights the potential benefits of using parathyroid scintigraphy in the initial workup of surgical patients.
AB - Secondary hyperparathyroidism (sHPT) is a major complication for patients with end-stage renal disease on long-term hemodialysis or peritoneal dialysis. When the disease is resistant to medical treatment, patients with severe sHPT are typically referred for parathyroidectomy (PTx), which usually improves biological parameters as well as clinical signs and symptoms. Unfortunately, early surgical failure with persistent disease may occur in 5%-10% of patients and recurrence reaches 20%-30% at 5 years. Presently, the use of parathyroid scintigraphy in sHPT is usually limited to the management of surgical failures after initial PTx. This review describes the strengths and limitations of typical 99mTc-sestamibi imaging protocols, and highlights the potential benefits of using parathyroid scintigraphy in the initial workup of surgical patients.
KW - Tc-MIBI
KW - dual isotope
KW - hemodialysis
KW - parathyroid scintigraphy
KW - secondary hyperparathyroidism
KW - surgery
KW - tertiary hyperparathyroidism
UR - http://www.scopus.com/inward/record.url?scp=84880746544&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880746544&partnerID=8YFLogxK
U2 - 10.1097/RLU.0b013e31829af5bf
DO - 10.1097/RLU.0b013e31829af5bf
M3 - Review article
C2 - 23751837
AN - SCOPUS:84880746544
SN - 0363-9762
VL - 38
SP - 630
EP - 635
JO - Clinical Nuclear Medicine
JF - Clinical Nuclear Medicine
IS - 8
ER -