Plasma Perfused over Immobilized Protein A for Breast Cancer

William I. Bensinger; Jean P. Kinet; Georges Hennen; Francis Franckenne; Charly Schaus; Michel Saint-Remy; Pierre Hoyoux; Philippe Mahieu; Thomas M.S. Chang; Thomas V. Holohan; Albert Deisseroth; David S. Terman; James B. Young; William T. Shearer; Carlos Ayus; Daniel E. Lehane; Henry I. Zaleski; Yerach Daskal

doi:10.1056/NEJM198204153061514

Plasma Perfused over Immobilized Protein A for Breast Cancer

William I. Bensinger, Jean P. Kinet, Georges Hennen, Francis Franckenne, Charly Schaus, Michel Saint-Remy, Pierre Hoyoux, Philippe Mahieu, Thomas M.S. Chang, Thomas V. Holohan, Albert Deisseroth, David S. Terman, James B. Young, William T. Shearer, Carlos Ayus, Daniel E. Lehane, Henry I. Zaleski, Yerach Daskal

Department of Medicine

Research output: Contribution to journal › Letter › peer-review

35 Scopus citations

Abstract

To the Editor: In the November 12 issue Terman et al. concluded that when plasma from patients with breast cancer was perfused over purified protein A immobilized in a collodion-charcoal matrix and subsequently reinfused, a partial remission was induced in three of five patients.¹ We report below our results in the same field. Five patients presenting with breast adenocarcinoma associated with metastatic lesions in bone or liver or both were treated five to 10 times with plasma perfusion over a column of silica covalently linked to 200 mg of purified protein A. Three of the patients were otherwise completely untreated,.

Original language	English (US)
Pages (from-to)	935-937
Number of pages	3
Journal	New England Journal of Medicine
Volume	306
Issue number	15
DOIs	https://doi.org/10.1056/NEJM198204153061514
State	Published - Apr 15 1982

ASJC Scopus subject areas

Medicine(all)

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Bensinger, W. I., Kinet, J. P., Hennen, G., Franckenne, F., Schaus, C., Saint-Remy, M., Hoyoux, P., Mahieu, P., Chang, T. M. S., Holohan, T. V., Deisseroth, A., Terman, D. S., Young, J. B., Shearer, W. T., Ayus, C., Lehane, D. E., Zaleski, H. I., & Daskal, Y. (1982). Plasma Perfused over Immobilized Protein A for Breast Cancer. New England Journal of Medicine, 306(15), 935-937. https://doi.org/10.1056/NEJM198204153061514

Bensinger, WI, Kinet, JP, Hennen, G, Franckenne, F, Schaus, C, Saint-Remy, M, Hoyoux, P, Mahieu, P, Chang, TMS, Holohan, TV, Deisseroth, A, Terman, DS, Young, JB, Shearer, WT, Ayus, C, Lehane, DE, Zaleski, HI & Daskal, Y 1982, 'Plasma Perfused over Immobilized Protein A for Breast Cancer', New England Journal of Medicine, vol. 306, no. 15, pp. 935-937. https://doi.org/10.1056/NEJM198204153061514

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title = "Plasma Perfused over Immobilized Protein A for Breast Cancer",

abstract = "To the Editor: In the November 12 issue Terman et al. concluded that when plasma from patients with breast cancer was perfused over purified protein A immobilized in a collodion-charcoal matrix and subsequently reinfused, a partial remission was induced in three of five patients.1 We report below our results in the same field. Five patients presenting with breast adenocarcinoma associated with metastatic lesions in bone or liver or both were treated five to 10 times with plasma perfusion over a column of silica covalently linked to 200 mg of purified protein A. Three of the patients were otherwise completely untreated,.",

author = "Bensinger, {William I.} and Kinet, {Jean P.} and Georges Hennen and Francis Franckenne and Charly Schaus and Michel Saint-Remy and Pierre Hoyoux and Philippe Mahieu and Chang, {Thomas M.S.} and Holohan, {Thomas V.} and Albert Deisseroth and Terman, {David S.} and Young, {James B.} and Shearer, {William T.} and Carlos Ayus and Lehane, {Daniel E.} and Zaleski, {Henry I.} and Yerach Daskal",

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day = "15",

doi = "10.1056/NEJM198204153061514",

language = "English (US)",

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T1 - Plasma Perfused over Immobilized Protein A for Breast Cancer

AU - Bensinger, William I.

AU - Kinet, Jean P.

AU - Hennen, Georges

AU - Franckenne, Francis

AU - Schaus, Charly

AU - Saint-Remy, Michel

AU - Hoyoux, Pierre

AU - Mahieu, Philippe

AU - Chang, Thomas M.S.

AU - Holohan, Thomas V.

AU - Deisseroth, Albert

AU - Terman, David S.

AU - Young, James B.

AU - Shearer, William T.

AU - Ayus, Carlos

AU - Lehane, Daniel E.

AU - Zaleski, Henry I.

AU - Daskal, Yerach

PY - 1982/4/15

Y1 - 1982/4/15

N2 - To the Editor: In the November 12 issue Terman et al. concluded that when plasma from patients with breast cancer was perfused over purified protein A immobilized in a collodion-charcoal matrix and subsequently reinfused, a partial remission was induced in three of five patients.1 We report below our results in the same field. Five patients presenting with breast adenocarcinoma associated with metastatic lesions in bone or liver or both were treated five to 10 times with plasma perfusion over a column of silica covalently linked to 200 mg of purified protein A. Three of the patients were otherwise completely untreated,.

AB - To the Editor: In the November 12 issue Terman et al. concluded that when plasma from patients with breast cancer was perfused over purified protein A immobilized in a collodion-charcoal matrix and subsequently reinfused, a partial remission was induced in three of five patients.1 We report below our results in the same field. Five patients presenting with breast adenocarcinoma associated with metastatic lesions in bone or liver or both were treated five to 10 times with plasma perfusion over a column of silica covalently linked to 200 mg of purified protein A. Three of the patients were otherwise completely untreated,.

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JO - New England Journal of Medicine

JF - New England Journal of Medicine

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ER -

Plasma Perfused over Immobilized Protein A for Breast Cancer

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