TY - JOUR
T1 - Point-of-care technologies for molecular diagnostics using a drop of blood
AU - Song, Yujun
AU - Huang, Yu Yen
AU - Liu, Xuewu
AU - Zhang, Xiaojing
AU - Ferrari, Mauro
AU - Qin, Lidong
PY - 2014/3
Y1 - 2014/3
N2 - Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.
AB - Molecular diagnostics is crucial for prevention, identification, and treatment of disease. Traditional technologies for molecular diagnostics using blood are limited to laboratory use because they rely on sample purification and sophisticated instruments, are labor and time intensive, expensive, and require highly trained operators. This review discusses the frontiers of point-of-care (POC) diagnostic technologies using a drop of blood obtained from a finger prick. These technologies, including emerging biotechnologies, nanotechnologies, and microfluidics, hold the potential for rapid, accurate, and inexpensive disease diagnostics.
KW - Biomolecules
KW - Circulating tumor cells
KW - Molecular diagnostics
KW - Nucleic acids
KW - Point-of-care diagnostics
KW - Proteins
UR - http://www.scopus.com/inward/record.url?scp=84894253862&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84894253862&partnerID=8YFLogxK
U2 - 10.1016/j.tibtech.2014.01.003
DO - 10.1016/j.tibtech.2014.01.003
M3 - Review article
C2 - 24525172
AN - SCOPUS:84894253862
SN - 0167-7799
VL - 32
SP - 132
EP - 139
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 3
ER -