TY - GEN
T1 - Reconstruction of central cortical surface from brain MRI images
T2 - 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
AU - Nie, Jingxin
AU - Liu, Tianming
AU - Guo, Lei
AU - Wong, Stephen T.C.
N1 - Funding Information:
This research is funded by a research grant to Dr. Stephen TC Wong by Harvard Center for Neurodegeneration and Repair, Harvard Medical School. Parts of the SPGR datasets are from NAMIC provided by the Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School. The high resolution MRI image is provided by the International Consortium for Brain Mapping (ICBM).
Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2007
Y1 - 2007
N2 - Reconstruction of the geometric central surface of the human cerebral cortex is an important means to study the structure and function of the brain cortex. In this paper, we propose a novel method based on an elastic deformable transform vector field to drive a deformable model for the reconstruction of the central surface of the brain cortex. In addition, simulated brain cortexes are generated to evaluate this method. We report the evaluation results obtained from ten subjects to show the effectiveness of our approach. We applied the central cortical surface reconstruction method and the hybrid cortical surface registration method to detect simulated brain atrophy. Our results indicate that the central cortical surface has much better sensitivity in detecting simulated atrophy than traditionally used inner or outer cortical surfaces.
AB - Reconstruction of the geometric central surface of the human cerebral cortex is an important means to study the structure and function of the brain cortex. In this paper, we propose a novel method based on an elastic deformable transform vector field to drive a deformable model for the reconstruction of the central surface of the brain cortex. In addition, simulated brain cortexes are generated to evaluate this method. We report the evaluation results obtained from ten subjects to show the effectiveness of our approach. We applied the central cortical surface reconstruction method and the hybrid cortical surface registration method to detect simulated brain atrophy. Our results indicate that the central cortical surface has much better sensitivity in detecting simulated atrophy than traditionally used inner or outer cortical surfaces.
KW - Atrophy detection
KW - Central cortical surface
KW - MRI images
UR - http://www.scopus.com/inward/record.url?scp=36348961313&partnerID=8YFLogxK
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U2 - 10.1109/ISBI.2007.356826
DO - 10.1109/ISBI.2007.356826
M3 - Conference contribution
AN - SCOPUS:36348961313
SN - 1424406722
SN - 9781424406722
T3 - 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
SP - 213
EP - 216
BT - 2007 4th IEEE International Symposium on Biomedical Imaging
Y2 - 12 April 2007 through 15 April 2007
ER -