Regulatory T cells and toll-like receptors in cancer therapy

Rong Fu Wang

doi:10.1158/0008-5472.CAN-05-4676

Regulatory T cells and toll-like receptors in cancer therapy

Rong Fu Wang

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.

Original language	English (US)
Pages (from-to)	4987-4990
Number of pages	4
Journal	Cancer research
Volume	66
Issue number	10
DOIs	https://doi.org/10.1158/0008-5472.CAN-05-4676
State	Published - May 15 2006

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1158/0008-5472.CAN-05-4676

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title = "Regulatory T cells and toll-like receptors in cancer therapy",

abstract = "T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.",

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AB - T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.

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JO - Cancer research

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Regulatory T cells and toll-like receptors in cancer therapy

Abstract

ASJC Scopus subject areas

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