Abstract
A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented. His clinical features included erythematous, edematous plaques and peripheral neuropathy. Reversal reactions are caused immunologically by enhanced cell-mediated (Th-1) immunity to Mycobacterium leprae, resulting in inflammation of infected tissues, such as skin and nerves. Acute neuritis can lead to permanent nerve damage and necessitate prompt treatment with prednisone and/or clofazamine.
| Original language | English |
|---|---|
| Title of host publication | J Drugs Dermatol |
| Pages | 70-71 |
| Number of pages | 2 |
| Volume | 1 |
| Edition | 1 |
| State | Published - Jul 1 2002 |