TY - JOUR
T1 - Rising trend of acute myocardial infarction among young cannabis users
T2 - A 10-year nationwide gender and race stratified analysis
AU - Sandhyavenu, Harigopal
AU - Patel, Harsh P.
AU - Patel, Riddhiben H.
AU - Desai, Rohan
AU - Patel, Achint A.
AU - Patel, Bhavin A.
AU - Patel, Jaimin
AU - Zahid, Salman
AU - Khan, Safi U.
AU - Deshmukh, Abhishek
AU - Nasir, Khurram
AU - DeSimone, Christopher V.
AU - Dani, Sourbha S.
AU - Thakkar, Samarthkumar
N1 - © 2023 The Authors.
PY - 2023/3
Y1 - 2023/3
N2 - BACKGROUND: The use of cannabis has massively increased among younger patients due to increasing legalization and availability.METHODS: We performed a retrospective nationwide study using the Nationwide inpatient sample (NIS) database to analyze the trends of acute myocardial infarction (AMI) in young cannabis users and related outcomes among patients aged 18-49 years from 2007 to 2018, using ICD-9 and ICD-10 codes.RESULTS: Out of 819,175 hospitalizations, 230,497 (28%) admissions reported using cannabis. There was a significantly higher number of males (78.08% vs. 71.58%, p < 0.0001) and African Americans (32.22% vs. 14.06%, p < 0.0001) admitted with AMI and reported cannabis use. The incidence of AMI among cannabis users consistently increased from 2.36% in 2007 to 6.55% in 2018. Similarly, the risk of AMI in cannabis users among all races increased, with the biggest increase in African Americans from 5.69% to 12.25%. In addition, the rate of AMI in cannabis users among both sexes showed an upward trend, from 2.63% to 7.17% in males and 1.62%-5.12% in females.CONCLUSION: The incidence of AMI in young cannabis users has increased in recent years. The risk is higher among males and African Americans.
AB - BACKGROUND: The use of cannabis has massively increased among younger patients due to increasing legalization and availability.METHODS: We performed a retrospective nationwide study using the Nationwide inpatient sample (NIS) database to analyze the trends of acute myocardial infarction (AMI) in young cannabis users and related outcomes among patients aged 18-49 years from 2007 to 2018, using ICD-9 and ICD-10 codes.RESULTS: Out of 819,175 hospitalizations, 230,497 (28%) admissions reported using cannabis. There was a significantly higher number of males (78.08% vs. 71.58%, p < 0.0001) and African Americans (32.22% vs. 14.06%, p < 0.0001) admitted with AMI and reported cannabis use. The incidence of AMI among cannabis users consistently increased from 2.36% in 2007 to 6.55% in 2018. Similarly, the risk of AMI in cannabis users among all races increased, with the biggest increase in African Americans from 5.69% to 12.25%. In addition, the rate of AMI in cannabis users among both sexes showed an upward trend, from 2.63% to 7.17% in males and 1.62%-5.12% in females.CONCLUSION: The incidence of AMI in young cannabis users has increased in recent years. The risk is higher among males and African Americans.
KW - Acute myocardial infarction
KW - Black adults
KW - Cannabis use
KW - Disparity
KW - Young
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U2 - 10.1016/j.ijcrp.2022.200167
DO - 10.1016/j.ijcrp.2022.200167
M3 - Article
C2 - 36874042
AN - SCOPUS:85147018495
SN - 2772-4875
VL - 16
SP - 200167
JO - International Journal of Cardiology: Cardiovascular Risk and Prevention
JF - International Journal of Cardiology: Cardiovascular Risk and Prevention
M1 - 200167
ER -