@inproceedings{8b054e77b8c64958bdd543fad2bf2408,
title = "Sensing of Bacillus Subtilis spores with peptide functionalized microcantilevers",
abstract = "Short peptide ligands were synthesized to selectively capture spores using microcantilever arrays. Our initial studies focused on the capture of Bacillus subtilis (a stimulant of Bacillus anthracis) spores in liquids. A peptide-ligand-functionalized microcantilever array was mounted on a flow cell filled with a B. subtilis suspension while cantilever deflection was monitored. Also, fifth mode resonant frequency measurements were performed before and after dipping a peptide-ligand-functionalized microcantilever array in a static B. subtilis solution. Both techniques showed selective binding to functionalized cantilevers when compared to arrays functionalized with a similar control (non-binding) peptide. Conclusive confirmation of selective binding was obtained by subsequent examination of the microcantilever arrays under a dark field microscope. The concentration sensitivity, shelf-life of the binding ligands, and their binding efficiency were studied as well.",
keywords = "Anthrax, Microcantilevers, Nano-bio-sensors, Peptides",
author = "Babita Dhayal and R. Reifenberger and Henne, {Walter A.} and Doorneweerd, {Derek D.} and Low, {Philip S.}",
year = "2006",
doi = "10.1109/nano.2006.247776",
language = "English (US)",
isbn = "1424400783",
series = "2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "787--789",
booktitle = "2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006",
address = "United States",
note = "2006 6th IEEE Conference on Nanotechnology, IEEE-NANO 2006 ; Conference date: 17-06-2006 Through 20-06-2006",
}