Abstract
The remarkable optical properties of surface-enhanced Raman scattering (SERS) has prompted the design and fabrication of SERS nanoparticles as biosensing and imaging labels. Among a variety of biosensing assay platforms within the growing point of care technology (POCT) field, lateral flow assay (LFA) has gained significant attention because of their simplicity, low cost, and user-friendly assay protocols. Herein, we show the development and performance benchmarking of SERS-based LFA for rapid and quantitative sensing of two important biomarkers: hCG and cTnT. The results suggest the feasibility of this platform for POCT applications.
Original language | English (US) |
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Article number | 9366787 |
Journal | IEEE Journal on Selected Topics in Quantum Electronics |
Volume | 27 |
Issue number | 5 |
DOIs | |
State | Published - Sep 1 2021 |
Keywords
- Laser biomedical applications
- lateral flow assay (LFA)
- nanotechnology
- plasmons
- surface enhanced raman scattering (SERS)
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electrical and Electronic Engineering