@article{5348b902ad184d47a7ca264a85b237d7,
title = "Shape Follows Function: Gastrointestinal Signals for Enterococcal Colonization",
abstract = "Vancomycin-resistant Enterococcus faecium (VRE) is a major cause of nosocomial infections. A new study by McKenney et al. (Cell Host Microbe 2019;25:695–705.e5) reports that VRE undergo a morphotype switch in response to lithocholic acid (LCA) to facilitate gastrointestinal (GI) tract colonization. This metabolic cue is a potential target to decrease VRE colonization and subsequent transmission of antibiotic resistance.",
keywords = "Enterococcus, GI colonization, VRE, antibiotic resistance, daptomycin",
author = "Nguyen, {April H.} and Miller, {William R.} and Arias, {Cesar A.}",
note = "Funding Information: C.A.A. is supported by National Institutes of Health (NIH)/ National Institutes of Allergy and Infectious Diseases (NIAID) grants K24 AI121296 , R01 AI134637 , and R21 AI143229 , and University of Texas System STARS Award and UTHealth Presidential Award. W.R.M. is supported by a K08 AI135093 award from NIH / NIAID . Funding Information: C.A.A. is supported by National Institutes of Health (NIH)/National Institutes of Allergy and Infectious Diseases (NIAID) grants K24 AI121296, R01 AI134637, and R21 AI143229, and University of Texas System STARS Award and UTHealth Presidential Award. W.R.M. is supported by a K08 AI135093 award from NIH/NIAID. W.R.M. has received grants from Merck and Entasis Therapeutics, and honoraria from Achaogen and Shionogi. C.A.A. has received grants from Merck, MeMed Diagnostics, and Entasis Therapeutics. Funding Information: W.R.M. has received grants from Merck and Entasis Therapeutics, and honoraria from Achaogen and Shionogi. C.A.A. has received grants from Merck, MeMed Diagnostics, and Entasis Therapeutics. Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",
year = "2019",
month = jun,
doi = "10.1016/j.molmed.2019.04.011",
language = "English (US)",
volume = "25",
pages = "464--466",
journal = "Trends in Molecular Medicine",
issn = "1471-4914",
publisher = "Elsevier Limited",
number = "6",
}