TY - JOUR
T1 - Soft-tissue reconstruction following extravasation of chemotherapeutic agents
AU - Shenaq, S. M.
AU - Abbase, E. H.A.
AU - Friedman, Jeffrey D.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 1996
Y1 - 1996
N2 - The incidence of chemotherapeutic extravasation injuries ranges from 0.5% to 6%. Chronicity and an indolent course are prominent characteristics of such wounds, as are severe pain and ulceration with no tendency to spontaneous healing. Prevention is the best treatment. Aggressive surgical debridement is recommended for patients with persistent pain or ulceration. Whirlpool therapy, wet-to-dry dressing changes, and a vigorous physical therapy program are all helpful. Soft-tissue coverage can be obtained by skin grafting, delayed flaps, various local muscle or fasciocutaneous flaps, or by free tissue transfer.
AB - The incidence of chemotherapeutic extravasation injuries ranges from 0.5% to 6%. Chronicity and an indolent course are prominent characteristics of such wounds, as are severe pain and ulceration with no tendency to spontaneous healing. Prevention is the best treatment. Aggressive surgical debridement is recommended for patients with persistent pain or ulceration. Whirlpool therapy, wet-to-dry dressing changes, and a vigorous physical therapy program are all helpful. Soft-tissue coverage can be obtained by skin grafting, delayed flaps, various local muscle or fasciocutaneous flaps, or by free tissue transfer.
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U2 - 10.1016/s1055-3207(18)30355-7
DO - 10.1016/s1055-3207(18)30355-7
M3 - Review article
C2 - 8899947
AN - SCOPUS:0029852226
SN - 1055-3207
VL - 5
SP - 825
EP - 845
JO - Surgical Oncology Clinics of North America
JF - Surgical Oncology Clinics of North America
IS - 4
ER -