SoLiD: Segmentation of clostridioides difficile cells in the presence of inhomogeneous illumination using a deep adversarial network

Ali Memariani, Ioannis A. Kakadiaris

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Segmentation of cells in scanning electron microscopy images is a challenging problem due to the presence of inhomogeneous illumination. Classical pre-processing methods for illumination normalization destroy the texture and add noise to the image. In this paper, we present a deep cell segmentation method using adversarial training that is robust to inhomogeneous illumination. Specifically, we apply a model based on U-net as the segmenter and a deep ConvNet as the discriminator for the adversarial training called SoLiD: “Segmentation of clostridioides difficile cells in the presence of inhomogeneous iLlumInation using a Deep adversarial network”. We also present an image augmentation algorithm to obtain the training images required for SoLid. The results indicate that SoLiD is robust to inhomogeneous illumination. The segmentation performance is compared to the U-net and the dice score is improved by 44%.

Original languageEnglish (US)
Title of host publicationMachine Learning in Medical Imaging - 9th International Workshop, MLMI 2018, Held in Conjunction with MICCAI 2018, Proceedings
EditorsMingxia Liu, Heung-Il Suk, Yinghuan Shi
PublisherSpringer-Verlag
Pages285-293
Number of pages9
ISBN (Print)9783030009182
DOIs
StatePublished - 2018
Event9th International Workshop on Machine Learning in Medical Imaging, MLMI 2018 held in conjunction with the 21st International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2018 - Granada, Spain
Duration: Sep 16 2018Sep 16 2018

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11046 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference9th International Workshop on Machine Learning in Medical Imaging, MLMI 2018 held in conjunction with the 21st International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2018
Country/TerritorySpain
CityGranada
Period9/16/189/16/18

Keywords

  • Cell segmentation
  • Data augmentation
  • Deep adversarial training
  • U-net

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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