TY - JOUR
T1 - Spinal epidural lipomatosis
T2 - Case reports, literature review and meta-analysis
AU - Fogel, Guy R.
AU - Cunningham, Paul Y.
AU - Esses, Stephen I.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/3
Y1 - 2005/3
N2 - Background context: Symptomatic spinal epidural lipomatosis (SEL), a rare cause of spinal cord compression, has most often been associated with exogenous steroid use. Purpose: Identify four associations with SE L, correlate the associated groups with level of disease and compare treatment with outcome data in these groups. Study design/setting: Case reports of three patients and analysis of 104 cases from the literature. Patient sample: Three patients from the senior author's practice. Outcome measures: Not applicable. Methods: The authors report three new cases of SEL not associated with steroid use. They review all available English literature and present a table of all 104 reported cases. Results: The clinical course of three new patients is reported. Conclusions: Associated conditions are exogenous steroid use, obesity, endogenous steroid excess, and some remain idiopathic. Although SEL is a rare condition, our review of the literature reveals many more reported cases than previously thought. With increased awareness of this condition and improved imaging techniques, further studies of this disease should be undertaken.
AB - Background context: Symptomatic spinal epidural lipomatosis (SEL), a rare cause of spinal cord compression, has most often been associated with exogenous steroid use. Purpose: Identify four associations with SE L, correlate the associated groups with level of disease and compare treatment with outcome data in these groups. Study design/setting: Case reports of three patients and analysis of 104 cases from the literature. Patient sample: Three patients from the senior author's practice. Outcome measures: Not applicable. Methods: The authors report three new cases of SEL not associated with steroid use. They review all available English literature and present a table of all 104 reported cases. Results: The clinical course of three new patients is reported. Conclusions: Associated conditions are exogenous steroid use, obesity, endogenous steroid excess, and some remain idiopathic. Although SEL is a rare condition, our review of the literature reveals many more reported cases than previously thought. With increased awareness of this condition and improved imaging techniques, further studies of this disease should be undertaken.
KW - Dura mater/pathology
KW - Lipoma/complications/pathology/radiography/surgery
KW - Spinal cord compression/etiology
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U2 - 10.1016/j.spinee.2004.05.252
DO - 10.1016/j.spinee.2004.05.252
M3 - Review article
C2 - 15795966
AN - SCOPUS:14744295088
SN - 1529-9430
VL - 5
SP - 202
EP - 211
JO - Spine Journal
JF - Spine Journal
IS - 2
ER -