Abstract
Human polymorphonuclear leukocytes (PMNs) are the first line of defense against invading microorganisms. Although most invading bacteria are eliminated by PMNs, some have evolved complex strategies to prevent normal PMN function. This review focuses on the interaction of human PMNs with Streptococcus pyogenes as a paradigm for successful pathogen evasion mechanisms.
Original language | English (US) |
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Pages (from-to) | 1117-1123 |
Number of pages | 7 |
Journal | Microbes and Infection |
Volume | 6 |
Issue number | 12 |
DOIs | |
State | Published - Oct 2004 |
Keywords
- Apoptosis
- Innate immunity
- Neutrophils
- Phagocytosis
- Polymorphonuclear leukocytes
- Streptococcus pyogenes
ASJC Scopus subject areas
- Microbiology
- Infectious Diseases