Stroke-related restless legs syndrome: epidemiology, clinical characteristics, and pathophysiology

Xi Xi Wang; Ya Feng; Eng King Tan; William G. Ondo; Yun Cheng Wu

doi:10.1016/j.sleep.2022.02.001

Stroke-related restless legs syndrome: epidemiology, clinical characteristics, and pathophysiology

Xi Xi Wang, Ya Feng, Eng King Tan, William G. Ondo, Yun Cheng Wu

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Stroke-related restless legs syndrome (RLS) is one of stroke-related sleep disorders, which may be due to de novo RLS after stroke onset or an exacerbation of RLS symptoms after incident stroke. To date, the diagnostic rate of stroke-related RLS is low but it has a significant effect on patients' daily life and functional outcome. This review provides an overview of the epidemiology, clinical characteristics, pathophysiology, and impact on functional outcome of stroke-related RLS.

Original language	English (US)
Pages (from-to)	238-248
Number of pages	11
Journal	Sleep Medicine
Volume	90
DOIs	https://doi.org/10.1016/j.sleep.2022.02.001
State	Published - Feb 2022

Keywords

Anatomical considerations
Prevalence
Restless legs syndrome
Stroke
Stroke/complications
Humans
Restless Legs Syndrome
Sleep Wake Disorders/epidemiology

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.sleep.2022.02.001

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title = "Stroke-related restless legs syndrome: epidemiology, clinical characteristics, and pathophysiology",

abstract = "Stroke-related restless legs syndrome (RLS) is one of stroke-related sleep disorders, which may be due to de novo RLS after stroke onset or an exacerbation of RLS symptoms after incident stroke. To date, the diagnostic rate of stroke-related RLS is low but it has a significant effect on patients' daily life and functional outcome. This review provides an overview of the epidemiology, clinical characteristics, pathophysiology, and impact on functional outcome of stroke-related RLS.",

keywords = "Anatomical considerations, Prevalence, Restless legs syndrome, Stroke, Stroke/complications, Humans, Restless Legs Syndrome, Sleep Wake Disorders/epidemiology",

author = "Wang, {Xi Xi} and Ya Feng and Tan, {Eng King} and Ondo, {William G.} and Wu, {Yun Cheng}",

note = "Funding Information: This work is supported by the Ministry of Science and Technology of the People's Republic of China Grant numbers ( 2021ZD0201900 ; 2021ZD0201905 ), National Natural Science Foundation of China ( 82171243 ; 81971185 ). Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

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doi = "10.1016/j.sleep.2022.02.001",

language = "English (US)",

volume = "90",

pages = "238--248",

journal = "Sleep Medicine",

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T1 - Stroke-related restless legs syndrome

T2 - epidemiology, clinical characteristics, and pathophysiology

AU - Wang, Xi Xi

AU - Feng, Ya

AU - Tan, Eng King

AU - Ondo, William G.

AU - Wu, Yun Cheng

N1 - Funding Information: This work is supported by the Ministry of Science and Technology of the People's Republic of China Grant numbers ( 2021ZD0201900 ; 2021ZD0201905 ), National Natural Science Foundation of China ( 82171243 ; 81971185 ). Publisher Copyright: © 2022 Elsevier B.V.

PY - 2022/2

Y1 - 2022/2

N2 - Stroke-related restless legs syndrome (RLS) is one of stroke-related sleep disorders, which may be due to de novo RLS after stroke onset or an exacerbation of RLS symptoms after incident stroke. To date, the diagnostic rate of stroke-related RLS is low but it has a significant effect on patients' daily life and functional outcome. This review provides an overview of the epidemiology, clinical characteristics, pathophysiology, and impact on functional outcome of stroke-related RLS.

AB - Stroke-related restless legs syndrome (RLS) is one of stroke-related sleep disorders, which may be due to de novo RLS after stroke onset or an exacerbation of RLS symptoms after incident stroke. To date, the diagnostic rate of stroke-related RLS is low but it has a significant effect on patients' daily life and functional outcome. This review provides an overview of the epidemiology, clinical characteristics, pathophysiology, and impact on functional outcome of stroke-related RLS.

KW - Anatomical considerations

KW - Prevalence

KW - Restless legs syndrome

KW - Stroke

KW - Stroke/complications

KW - Humans

KW - Restless Legs Syndrome

KW - Sleep Wake Disorders/epidemiology

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U2 - 10.1016/j.sleep.2022.02.001

DO - 10.1016/j.sleep.2022.02.001

M3 - Review article

C2 - 35219214

AN - SCOPUS:85125122289

SN - 1389-9457

VL - 90

SP - 238

EP - 248

JO - Sleep Medicine

JF - Sleep Medicine

ER -

Stroke-related restless legs syndrome: epidemiology, clinical characteristics, and pathophysiology

Abstract

Keywords

ASJC Scopus subject areas

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