TY - JOUR
T1 - Tetras spirals and handwriting samples
T2 - Determination of optimal scoring examples
AU - Ondo, William G.
AU - Shukla, Aparna Wagle
AU - Ondo, Carson
N1 - Funding Information:
William Ondo MD: Honorarium for speaking bureau from: TEVA, ACADIA, Acorda, ADAMAS, Neurocrine, UCBPharma, USWorldMeds, and Sunovion. He has received research grants from Biogen, Lundbeck, Sun, Restless Legs Syndrome Foundation, Parkinson’s Study Group, Sun, Biogen, Ceravel and Revance. Consulting fees: Takeda, Merz, Jazz, XWPharma, Neurocrine, Emalex. Royalties: from the books Restless Legs Syndrome, Movement Disorders in Clinical Practice, and UpToDate. Aparna Wagle Shukla MD: grant support from the NIH and has received grant support from Benign Essential Blepharospasm Research foundation, Dystonia coalition, Dystonia Medical Research foundation, National Organization for Rare Disorders and grant support from NIH (KL2 and K23 NS092957-01A1) as a PI. She receives support from NIH Ro1 R01NS121120-01 as a Co-I. Consultant fees from Merz and Acadia. She is the current Vice President for the Tremor Research Group.
Funding Information:
William Ondo MD: Honorarium for speaking bureau from: TEVA, ACADIA, Acorda, ADAMAS, Neurocrine, UCBPharma, USWorldMeds, and Sunovion. He has received research grants from Biogen, Lundbeck, Sun, Restless Legs Syndrome Foundation, Parkinson?s Study Group, Sun, Biogen, Ceravel and Revance. Consulting fees: Takeda, Merz, Jazz, XWPharma, Neurocrine, Emalex. Royalties: from the books Restless Legs Syndrome, Movement Disorders in Clinical Practice, and UpToDate. Aparna Wagle Shukla MD: grant support from the NIH and has received grant support from Benign Essential Blepharospasm Research foundation, Dystonia coalition, Dystonia Medical Research foundation, National Organization for Rare Disorders and grant support from NIH (KL2 and K23 NS092957-01A1) as a PI. She receives support from NIH Ro1 R01NS121120-01 as a Co-I. Consultant fees from Merz and Acadia. She is the current Vice President for the Tremor Research Group.
Publisher Copyright:
© 2021 The Author(s).
PY - 2021
Y1 - 2021
N2 - Background: Spiral drawings and handwriting tasks have long been used to assess the severity of essential tremor, but these motor tasks are somewhat less objective as the rules for scoring are not based on firm objective amplitude-based criteria. Publishing the best examples of each of the possible 0–4 ratings for these items could reduce scoring variance. Methods: 21 members of the Tremor Research Group each rated 94 spirals and 64 handwriting samples using TETRAS scoring criteria. For each sample, the most frequently reported score (mode; maximum of 21) was determined. Ratings not adjacent to the mode were subtracted from the number of mode scores, to calculate a total value. For each of the ratings (0, 1, 1.5, 2, 2.5, 3, 3.5, 4), the samples with the highest total value were selected as best examples. Results: In general, rater agreement was good for spirals but poor for handwriting samples. Nevertheless, examples with excellent agreement were identified for all spiral and handwriting ratings, and are presented. Conclusion: Best examples for scoring spirals and handwritings are needed to reduce the variance of TETRAS scores in clinical trials and clinical practice.
AB - Background: Spiral drawings and handwriting tasks have long been used to assess the severity of essential tremor, but these motor tasks are somewhat less objective as the rules for scoring are not based on firm objective amplitude-based criteria. Publishing the best examples of each of the possible 0–4 ratings for these items could reduce scoring variance. Methods: 21 members of the Tremor Research Group each rated 94 spirals and 64 handwriting samples using TETRAS scoring criteria. For each sample, the most frequently reported score (mode; maximum of 21) was determined. Ratings not adjacent to the mode were subtracted from the number of mode scores, to calculate a total value. For each of the ratings (0, 1, 1.5, 2, 2.5, 3, 3.5, 4), the samples with the highest total value were selected as best examples. Results: In general, rater agreement was good for spirals but poor for handwriting samples. Nevertheless, examples with excellent agreement were identified for all spiral and handwriting ratings, and are presented. Conclusion: Best examples for scoring spirals and handwritings are needed to reduce the variance of TETRAS scores in clinical trials and clinical practice.
KW - Spiral
KW - TETRAS
KW - Tremor
KW - Writing
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UR - http://www.scopus.com/inward/citedby.url?scp=85121140550&partnerID=8YFLogxK
U2 - 10.5334/TOHM.665
DO - 10.5334/TOHM.665
M3 - Article
C2 - 34820149
AN - SCOPUS:85121140550
SN - 2160-8288
VL - 11
SP - 1
EP - 6
JO - Tremor and Other Hyperkinetic Movements
JF - Tremor and Other Hyperkinetic Movements
ER -