The mechanism of lipid-binding by plasma lipoproteins

Richard L. Jackson; Joel D. Morrisett; Antonio Gotto; Jere P. Segrest

doi:10.1007/BF01731865

The mechanism of lipid-binding by plasma lipoproteins

Richard L. Jackson, Joel D. Morrisett, Antonio Gotto, Jere P. Segrest

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

Abstract

In this article, we review the current state of knowledge about the structure of human plasma high density lipoproteins. Recent advances in this field, including amino acid sequencing and lipid-binding studies, suggest that the plasma lipoproteins have specific sites with special structural features that account for their ability to bind and transport lipid. A hypothesis which describes the structure of these lipid-binding sites and their interaction with lipid is presented.

Original language	English (US)
Pages (from-to)	43-50
Number of pages	8
Journal	Molecular and Cellular Biochemistry
Volume	6
Issue number	1
DOIs	https://doi.org/10.1007/BF01731865
State	Published - Jan 1 1975

ASJC Scopus subject areas

Molecular Biology
Clinical Biochemistry
Cell Biology

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10.1007/BF01731865

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abstract = "In this article, we review the current state of knowledge about the structure of human plasma high density lipoproteins. Recent advances in this field, including amino acid sequencing and lipid-binding studies, suggest that the plasma lipoproteins have specific sites with special structural features that account for their ability to bind and transport lipid. A hypothesis which describes the structure of these lipid-binding sites and their interaction with lipid is presented.",

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AB - In this article, we review the current state of knowledge about the structure of human plasma high density lipoproteins. Recent advances in this field, including amino acid sequencing and lipid-binding studies, suggest that the plasma lipoproteins have specific sites with special structural features that account for their ability to bind and transport lipid. A hypothesis which describes the structure of these lipid-binding sites and their interaction with lipid is presented.

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The mechanism of lipid-binding by plasma lipoproteins

Abstract

ASJC Scopus subject areas

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