Therapeutic and donor apheresis

Jill Adamski; Tina S. Ipe; Theresa Kinard

doi:10.1016/B978-0-12-803999-1.00014-6

Therapeutic and donor apheresis

Jill Adamski, Tina S. Ipe, Theresa Kinard

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Abstract

Apheresis machines separate whole blood into cellular and plasma fractions. This allows for therapeutic interventions through removal of pathologic substances from these fractions (e.g., therapeutic plasma exchange to remove acetylcholine receptor antibodies in patients with myasthenia gravis) or by isolation and treatment of a specific blood component (e.g., collection and photoactivation of WBCs to induce immunomodulation by extracorporeal photopheresis). Apheresis procedures are also used to collect blood products for transfusion and hematopoietic progenitor cells for transplant. This chapter focuses on the basic principles of apheresis procedures, indications for therapeutic apheresis that are supported by evidence-based guidelines, and the management of adverse events associated with these procedures.

Original language	English (US)
Title of host publication	Transfusion Medicine, Apheresis, and Hemostasis
Subtitle of host publication	Review Questions and Case Studies
Editors	Huy Pham, Lance Williams, III
Publisher	Elsevier
Chapter	14
Pages	327-351
Number of pages	25
Edition	1st
ISBN (Electronic)	9780128039991
ISBN (Print)	9780128040300
DOIs	https://doi.org/10.1016/B978-0-12-803999-1.00014-6
State	Published - Sep 20 2017

Keywords

Citrate toxicity
Plasmapheresis
Red blood cell exchange
Stem cell collection
Therapeutic plasma exchange

ASJC Scopus subject areas

Medicine (miscellaneous)

Access to Document

10.1016/B978-0-12-803999-1.00014-6

Cite this

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Therapeutic and donor apheresis

Abstract

Keywords

ASJC Scopus subject areas

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