Tissue-cultured smooth muscle cells from normal and atherosclerotic arteries

S. G. Eskin; H. D. Sybers; L. T. Navarro; Antonio Gotto; M. E. DeBakey

Tissue-cultured smooth muscle cells from normal and atherosclerotic arteries

S. G. Eskin, H. D. Sybers, L. T. Navarro, Antonio Gotto, M. E. DeBakey

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

One hypothesis put forth to explain atherogenesis is that the lesions originate with neoplastically transformed smooth muscle cells (SMC) in the vessel wall. If this is so, SMC derived from lesions may exhibit transformed behavior in tissue culture, for example, a capacity to replicate infinitely and a rapid rate of proliferation compared to cells derived from uninvolved vessel wall.

Original language	English
Title of host publication	Cardiovascular Research Center Bulletin
Pages	85-89
Number of pages	5
Volume	18
Edition	4
State	Published - Dec 1 1980

ASJC Scopus subject areas

Medicine(all)

Cite this

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abstract = "One hypothesis put forth to explain atherogenesis is that the lesions originate with neoplastically transformed smooth muscle cells (SMC) in the vessel wall. If this is so, SMC derived from lesions may exhibit transformed behavior in tissue culture, for example, a capacity to replicate infinitely and a rapid rate of proliferation compared to cells derived from uninvolved vessel wall.",

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AU - Gotto, Antonio

AU - DeBakey, M. E.

PY - 1980/12/1

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AB - One hypothesis put forth to explain atherogenesis is that the lesions originate with neoplastically transformed smooth muscle cells (SMC) in the vessel wall. If this is so, SMC derived from lesions may exhibit transformed behavior in tissue culture, for example, a capacity to replicate infinitely and a rapid rate of proliferation compared to cells derived from uninvolved vessel wall.

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Tissue-cultured smooth muscle cells from normal and atherosclerotic arteries

Abstract

ASJC Scopus subject areas

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