TY - JOUR
T1 - Tropical Spastic Paraparesis
T2 - HTLV-I Antibodies in Patients from the Seychelles
AU - Roman, Gustavo C.
AU - Spencer, Peter S.
AU - Schoenberg, Bruce S.
AU - Madden, David
AU - Sever, John
AU - Hugon, Jacques
AU - Ludolph, Albert
PY - 1987/1/1
Y1 - 1987/1/1
N2 - To the Editor: HTLV-I-associated myelopathies have been reported in Japan1 and the Caribbean basin.2,3 We studied HTLV-I antibodies in serum samples from patients with tropical spastic paraparesis who were from the Seychelles Islands; we used the Bioteck enzyme-linked immunosorbent assay and an indirect fluorescent antibody test, together with HTLV-I antigen grown in HUT 102 cells. Of 20 patients with tropical spastic paraparesis diagnosed by strict criteria, 17 (85 percent) were positive for HTLV-I antibodies. Nine neurologically normal controls and five patients with other neurologic diseases were negative for HTLV-I antibodies. HTLV-I antibodies were found in one patient in the control…, No extract is available for articles shorter than 400 words.
AB - To the Editor: HTLV-I-associated myelopathies have been reported in Japan1 and the Caribbean basin.2,3 We studied HTLV-I antibodies in serum samples from patients with tropical spastic paraparesis who were from the Seychelles Islands; we used the Bioteck enzyme-linked immunosorbent assay and an indirect fluorescent antibody test, together with HTLV-I antigen grown in HUT 102 cells. Of 20 patients with tropical spastic paraparesis diagnosed by strict criteria, 17 (85 percent) were positive for HTLV-I antibodies. Nine neurologically normal controls and five patients with other neurologic diseases were negative for HTLV-I antibodies. HTLV-I antibodies were found in one patient in the control…, No extract is available for articles shorter than 400 words.
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U2 - 10.1056/NEJM198701013160113
DO - 10.1056/NEJM198701013160113
M3 - Letter
C2 - 2878366
AN - SCOPUS:0023090417
SN - 0028-4793
VL - 316
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 1
ER -