Abstract
We report a novel microfluidic sensing platform enabled by disk-shaped nanoporous gold nanoparticles (NPGNs), representing a unique class of hierarchical plasmonic nanoparticle. NPGNs possess large specific surface area and high-density, internal plasmonic "hot-spots" with impressive electric field enhancement, which greatly promotes plasmon-matter interaction as evidenced by spectral shifts in the surface plasmon resonance. In addition, the plasmonic resonance of disk-shaped NPGNs can be easily tuned from 900 to 1850 nm by changing the disk diameter from 300 to 700 nm. By surface-enhanced Raman scattering, we demonstrate label-free sensing of biomolecules and in situ monitoring of individual DNA hybridization.
| Original language | English (US) |
|---|---|
| Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 1823-1825 |
| Number of pages | 3 |
| ISBN (Print) | 9780979806476 |
| State | Published - 2014 |
| Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States Duration: Oct 26 2014 → Oct 30 2014 |
Other
| Other | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
|---|---|
| Country/Territory | United States |
| City | San Antonio |
| Period | 10/26/14 → 10/30/14 |
Keywords
- Label-free
- Molecular sensing
- Plasmonics
- SERS
ASJC Scopus subject areas
- Control and Systems Engineering