Abstract
Institutionalized and community-dwelling older adults have been greatly impacted by the coronavirus disease 2019 (COVID-19) pandemic with increased morbidity and mortality. The advent of vaccines and their widespread use in this population has brought about a dramatic turnaround in COVID-19 outcomes. The immunogenicity and effectiveness of the various vaccine options worldwide are discussed. Optimization of vaccine usage will still be important to maximize protection due to reduced initial immunity, development of variant strains, and fading of immunity over time. There are also lessons learned specific to older populations for future pandemics of novel pathogens.
Original language | English (US) |
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Pages (from-to) | 27-45 |
Number of pages | 19 |
Journal | Infectious Disease Clinics of North America |
Volume | 37 |
Issue number | 1 |
DOIs | |
State | Published - Mar 2023 |
Keywords
- Aging
- COVID-19 vaccine
- Geriatric
- Immunogenicity
- Older adults
- Vaccine effectiveness
- SARS-CoV-2
- Humans
- COVID-19/prevention & control
- Aged
- Vaccines
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases