Projects per year
Search results
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Active
REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy
Niravath, P. A. (PI), Antosh, D. (Key Personnel), Chaaya, G. (Key Personnel), Chang, J. C. (Key Personnel), High, R. A. (Key Personnel), Mai, H. P. (Key Personnel), Singh, M. (Key Personnel), Sun, K. (Key Personnel) & Zaid, T. (Key Personnel)
5/17/24 → …
Project: Clinical Trial
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Texas Southern University Breast Cancer Prevention and Screening Center (TSU BCSPC)
Niravath, P. A. (PI)
10/1/21 → 2/28/25
Project: State
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Fulvestrant Plus Abemaciclib With or Without Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer
Chang, J. C. (PI), Mai, H. P. (Key Personnel), Mathur, S. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)
7/15/21 → …
Project: Clinical Trial
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Nanotechnology-based targeting of breast cancer liver metastases
Godin, B. (PI), Chen, S.-H. (Key Personnel), Niravath, P. A. (Key Personnel), Rosato, R. R. (Key Personnel) & Xu, S. (Key Personnel)
3/1/21 → 2/28/25
Project: Federal Funding Agencies
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Multicenter Phase I/Ib Trial of Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer
Chang, J. C. (PI), Chaaya, G. (Key Personnel), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)
2/9/21 → …
Project: Clinical Trial
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The use of mobile health technology to improve breast and prostate cancer survivors' health behaviors in managing their weight and lifestyle
Stubbins, R. E. (PI), Niravath, P. A. (Key Personnel), Satkunasivam, R. (Key Personnel) & Wong, S. T. (Key Personnel)
1/25/21 → …
Project: Clinical Trial
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Sample and Data Collection for Houston Methodist Cancer Center Research
Chang, J. C. (PI), Bernicker, E. H. (Key Personnel), Darcourt, J. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
4/9/20 → …
Project: Clinical Trial
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ALLIANCE A221602: OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
Darcourt, J. (PI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Geyer, C. E. (CoI), Heyne, K. (CoI) & Niravath, P. A. (CoI)
3/6/20 → 3/5/45
Project: Non Profit
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CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.
Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)
3/6/20 → 3/5/45
Project: Non Profit
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NRG-BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer
Geyer, C. E. (PI), Niravath, P. A. (PI), Chang, J. C. (CoI) & Darcourt, J. (CoI)
3/12/19 → 2/28/25
Project: Non Profit
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TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE AND T3N0 BREAST CANCER
Teh, B. S. (PI), Chang, J. C. (CoI), Farach, A. M. (CoI), Haque, W. M. (CoI), Morgan, P. B. (CoI), Niravath, P. A. (CoI), Shadle, K. M. (CoI), Shkedy, C. (CoI) & Singh, M. (CoI)
5/30/18 → 5/29/28
Project: Non Profit
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A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL
Arentz, C. (PI), Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)
12/8/16 → 12/7/41
Project: Non Profit
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Metastatic Stem Cells-ROLE OF CANCER STEM CELLS IN BREAST CANCER RECURRENCE AND METASTASIS
Chang, J. C. (PI), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
3/20/14 → …
Project: Clinical Trial
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Stem Cell: Biomarkers Including Putative Stem Cells Markers in Human Breast Cancers
Chang, J. C. (PI), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)
3/20/14 → …
Project: Clinical Trial
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Not started
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (PRESERVE-001)
Chang, J. C. (PI), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)
Project: Clinical Trial
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Acupuncture Trial
Niravath, P. A. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Mai, H. P. (Key Personnel), Singh, M. (Key Personnel) & Sun, K. (Key Personnel)
Project: Clinical Trial
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Multicenter Phase II Trial of Durvalumab (MEDI4736) With Trastuzumab and Pertuzumab Combination in HER2-Enriched and HER2-Amplified Breast Cancer (DTP Trial)
Chang, J. C. (PI), Arentz, C. (Key Personnel), Chaaya, G. (Key Personnel), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)
Project: Clinical Trial
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PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2
Niravath, P. A. (PI), Chang, J. C. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo
Niravath, P. A. (PI), Abdelrahim, M. (Key Personnel), Arentz, C. (Key Personnel), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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BO41843: Phase III_GDC-9545 RO7197597_Breast Cancer_Roche BO41843: A Phase III Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Patients With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
Niravath, P. A. (PI), Chang, J. C. (Key Personnel), Mai, H. P. (Key Personnel) & Sun, K. (Key Personnel)
Project: Clinical Trial
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DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane
Niravath, P. A. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
Sun, K. (PI), Chang, J. C. (Key Personnel), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Templeton, S. (Key Personnel)
Project: Clinical Trial
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A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared With Investigator Choice in HLA-A*0201 Positive Patients With Previously Untreated Advanced Uveal Melanoma
Abdelrahim, M. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma
Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)
Project: Clinical Trial
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Clinical Phase Ib/II Trial of L-NMMA Plus Docetaxel in the Treatment of Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients
Niravath, P. A. (PI), Beinart, G. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy
Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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(PENELOPE-B) GBG-78 - BIG 1-13 - NSABP-B-54-I A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery
Chang, J. C. (PI), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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CardOnc screening
Bhimaraj, A. (Key Personnel), Guha, A. (Key Personnel), Niravath, P. A. (Key Personnel) & Pingali, S. R. (Key Personnel)
Project: Clinical Trial
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A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative
Niravath, P. A. (PI), Butler, E. B. (Key Personnel), Chang, J. C. (Key Personnel), Farach, A. M. (Key Personnel), Haque, W. M. (Key Personnel), Heyne, K. (Key Personnel), Morgan, P. B. (Key Personnel) & Teh, B. S. (Key Personnel)
Project: Clinical Trial
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A Pilot Study of Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention In Women At High Risk Of Breast Cancer
Chang, J. C. (PI), Arentz, C. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)
Project: Clinical Trial
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A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy
Templeton, S. (PI), Arentz, C. (Key Personnel), Chang, J. C. (Key Personnel), Darcourt, J. (Key Personnel), Dubrovsky, E. (Key Personnel), Haque, W. M. (Key Personnel), Heyne, K. (Key Personnel), Morgan, P. B. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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Converting HR Breast Cancer Into an Individualized Vaccine
Chang, J. C. (PI), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)
Project: Clinical Trial
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Randomized Study of Erlotinib vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)
Zhang, J. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma
Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)
Project: Clinical Trial
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Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer (INTEGRAL)
Chang, J. C. (PI), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel), Sun, K. (Key Personnel) & Venta, L. A. (Key Personnel)
Project: Clinical Trial
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A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in Participants With High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease in Breast
Mai, H. P. (PI), Chaaya, G. (Key Personnel), Chang, J. C. (Key Personnel), Niravath, P. A. (Key Personnel), Sun, K. (Key Personnel) & Templeton, S. (Key Personnel)
Project: Clinical Trial
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Katherine, B50, for Treatment of Adjuvant HER2 Positive Breast Cancer
Chang, J. C. (PI), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)
Project: Clinical Trial
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Finished
Converting HR+ Breast Cancer Into an Individualized Vaccine
Chang, J. C. (PI), Darcourt, J. (CoI) & Niravath, P. A. (CoI)
9/30/19 → 9/30/23
Project: Federal Funding Agencies
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A Phase 0, Investigator Initiated Study, Evaluating the Impact of Omega 3 Free Fatty Acid Supplementation on Aromatase in Obese Subjects (CTMS# 15-2100)
Niravath, P. A. (PI), Chang, J. C. (CoI) & Darcourt, J. (CoI)
12/1/16 → 11/30/18
Project: Federal Funding Agencies
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Multimodal MRI Biomarker of Mild Cognitive Impairment in Breast Cancer
Niravath, P. A. (PI), Chang, J. C. (CoI) & Darcourt, J. (CoI)
9/26/16 → 6/30/18
Project: Federal Funding Agencies