Abstract
Background. Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10% of all sarcomas. They arise from unknown pleuripotent stem cells that are capable of differentiating into mesenchymal and/or epithelial structures. Synovial sarcoma is characterized by specific chromosomal translocation t (X; 18)(p11, q11). Case. We report the first case of monophasic synovial sarcoma arising in soft tissues of the vulva in a 33-year-old female. Complete excision of the mass was possible with tumor-free margins. Conclusion. Only four previous cases of biphasic synovial sarcoma arising in the vulva have been reported. The finding of the SYT-SSX2 translocation is generally associated with a better prognosis, besides tumor negative margins after excision offer the possibility of a better outlook for this patient.
Original language | English (US) |
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Pages (from-to) | 433-436 |
Number of pages | 4 |
Journal | Gynecologic oncology |
Volume | 100 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2006 |
Keywords
- Monophasic
- Synovial sarcoma
- Translocation t (X, 18)(p11, q11)
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Oncology