Bicuspid Aortic Valve Disease: Classifications, Treatments, and Emerging Transcatheter Paradigms

Ankur Kalra; Rajiv Das; Mohammad Alkhalil; Iryna Dykun; Alessandro Candreva; Omar Jarral; Syed M. Rehman; Monil Majmundar; Kunal N. Patel; Josep Rodes-Cabau; Michael J. Reardon; Rishi Puri

doi:10.1016/j.shj.2023.100227

Bicuspid Aortic Valve Disease: Classifications, Treatments, and Emerging Transcatheter Paradigms

Ankur Kalra, Rajiv Das, Mohammad Alkhalil, Iryna Dykun, Alessandro Candreva, Omar Jarral, Syed M. Rehman, Monil Majmundar, Kunal N. Patel, Josep Rodes-Cabau, Michael J. Reardon, Rishi Puri

Research output: Contribution to journal › Review article › peer-review

Abstract

Bicuspid aortic valve (BAV) is a common congenital valvular malformation, which may lead to early aortic valve disease and bicuspid-associated aortopathy. A novel BAV classification system was recently proposed to coincide with transcatheter aortic valve replacement being increasingly considered in younger patients with symptomatic BAV, with good clinical results, yet without randomized trial evidence. Procedural technique, along with clinical outcomes, have considerably improved in BAV patients compared with tricuspid aortic stenosis patients undergoing transcatheter aortic valve replacement. The present review summarizes the novel BAV classification systems and examines contemporary surgical and transcatheter approaches.

Original language	English (US)
Article number	100227
Pages (from-to)	100227
Journal	Structural Heart
Volume	8
Issue number	1
DOIs	https://doi.org/10.1016/j.shj.2023.100227
State	Published - Jan 2024

Keywords

Aortic stenosis
Bicuspid aortic valve
Surgical aortic valve replacement
Transcatheter aortic valve replacement

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.shj.2023.100227

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title = "Bicuspid Aortic Valve Disease: Classifications, Treatments, and Emerging Transcatheter Paradigms",

abstract = "Bicuspid aortic valve (BAV) is a common congenital valvular malformation, which may lead to early aortic valve disease and bicuspid-associated aortopathy. A novel BAV classification system was recently proposed to coincide with transcatheter aortic valve replacement being increasingly considered in younger patients with symptomatic BAV, with good clinical results, yet without randomized trial evidence. Procedural technique, along with clinical outcomes, have considerably improved in BAV patients compared with tricuspid aortic stenosis patients undergoing transcatheter aortic valve replacement. The present review summarizes the novel BAV classification systems and examines contemporary surgical and transcatheter approaches.",

keywords = "Aortic stenosis, Bicuspid aortic valve, Surgical aortic valve replacement, Transcatheter aortic valve replacement",

author = "Ankur Kalra and Rajiv Das and Mohammad Alkhalil and Iryna Dykun and Alessandro Candreva and Omar Jarral and Rehman, {Syed M.} and Monil Majmundar and Patel, {Kunal N.} and Josep Rodes-Cabau and Reardon, {Michael J.} and Rishi Puri",

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year = "2024",

month = jan,

doi = "10.1016/j.shj.2023.100227",

language = "English (US)",

volume = "8",

pages = "100227",

journal = "Structural Heart",

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T2 - Classifications, Treatments, and Emerging Transcatheter Paradigms

AU - Kalra, Ankur

AU - Das, Rajiv

AU - Alkhalil, Mohammad

AU - Dykun, Iryna

AU - Candreva, Alessandro

AU - Jarral, Omar

AU - Rehman, Syed M.

AU - Majmundar, Monil

AU - Patel, Kunal N.

AU - Rodes-Cabau, Josep

AU - Reardon, Michael J.

AU - Puri, Rishi

PY - 2024/1

Y1 - 2024/1

N2 - Bicuspid aortic valve (BAV) is a common congenital valvular malformation, which may lead to early aortic valve disease and bicuspid-associated aortopathy. A novel BAV classification system was recently proposed to coincide with transcatheter aortic valve replacement being increasingly considered in younger patients with symptomatic BAV, with good clinical results, yet without randomized trial evidence. Procedural technique, along with clinical outcomes, have considerably improved in BAV patients compared with tricuspid aortic stenosis patients undergoing transcatheter aortic valve replacement. The present review summarizes the novel BAV classification systems and examines contemporary surgical and transcatheter approaches.

AB - Bicuspid aortic valve (BAV) is a common congenital valvular malformation, which may lead to early aortic valve disease and bicuspid-associated aortopathy. A novel BAV classification system was recently proposed to coincide with transcatheter aortic valve replacement being increasingly considered in younger patients with symptomatic BAV, with good clinical results, yet without randomized trial evidence. Procedural technique, along with clinical outcomes, have considerably improved in BAV patients compared with tricuspid aortic stenosis patients undergoing transcatheter aortic valve replacement. The present review summarizes the novel BAV classification systems and examines contemporary surgical and transcatheter approaches.

KW - Aortic stenosis

KW - Bicuspid aortic valve

KW - Surgical aortic valve replacement

KW - Transcatheter aortic valve replacement

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ER -

Bicuspid Aortic Valve Disease: Classifications, Treatments, and Emerging Transcatheter Paradigms

Abstract

Keywords

ASJC Scopus subject areas

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