Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons

Rana A. Hajjeh; Laura A. Conn; David S. Stephens; Wendy Baughman; Richard Hamill; Edward Graviss; Peter G. Pappas; Carolynn Thomas; Arthur Reingold; Gretchen Rothrock; Lori C. Hutwagner; Anne Schuchat; Mary E. Brandt; Robert W. Pinner; Monica Farley; Molly Bardsley; Betsy Siegel; Georgia Jackson; Chris Lao; Jodie Otte; Christopher Harvey; David Rimland; Roger Gillespie; Bharat Pattni; Pam Daily; Nivin Shihata; Elias Durry

doi:10.1086/314606

Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons

Rana A. Hajjeh, Laura A. Conn, David S. Stephens, Wendy Baughman, Richard Hamill, Edward Graviss, Peter G. Pappas, Carolynn Thomas, Arthur Reingold, Gretchen Rothrock, Lori C. Hutwagner, Anne Schuchat, Mary E. Brandt, Robert W. Pinner, Monica Farley, Molly Bardsley, Betsy Siegel, Georgia Jackson, Chris Lao, Jodie OtteChristopher Harvey, David Rimland, Roger Gillespie, Bharat Pattni, Pam Daily, Nivin Shihata, Elias Durry

Research output: Contribution to journal › Article › peer-review

234 Scopus citations

Abstract

To determine the incidence of cryptococcosis and its risk factors among human immunodeficiency virus (HIV)-infected persons, population-based active surveillance was conducted in four US areas (population, 12.5 million) during 1992-1994, and a case-control study was done. Of 1083 cases, 931 (86%) occurred in HIV-infected persons. The annual incidence of cryptococcosis per 1000 among persons living with AIDS ranged from 17 (San Francisco, 1994) to 66 (Atlanta, 1992) and decreased significantly in these cities during 1992- 1994. Among non-HIV-infected persons, the annual incidence of cryptococcosis ranged from 0.2 to 0.9/100.000. Multivariate analysis of the case-control study (158 cases and 423 controls) revealed smoking and outdoor occupations to be significantly associated with an increased risk of cryptococcosis; receiving fluconazole within 3 months before enrollment was associated with a decreased risk for cryptococcosis. Further studies are needed to better describe persons with AIDS currently developing cryptococcosis in the era of highly active antiretroviral therapy.

Original language	English (US)
Pages (from-to)	449-454
Number of pages	6
Journal	Journal of Infectious Diseases
Volume	179
Issue number	2
DOIs	https://doi.org/10.1086/314606
State	Published - 1999
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1086/314606

Cite this

Hajjeh, R. A., Conn, L. A., Stephens, D. S., Baughman, W., Hamill, R., Graviss, E., Pappas, P. G., Thomas, C., Reingold, A., Rothrock, G., Hutwagner, L. C., Schuchat, A., Brandt, M. E., Pinner, R. W., Farley, M., Bardsley, M., Siegel, B., Jackson, G., Lao, C., ... Durry, E. (1999). Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons. Journal of Infectious Diseases, 179(2), 449-454. https://doi.org/10.1086/314606

Hajjeh, RA, Conn, LA, Stephens, DS, Baughman, W, Hamill, R, Graviss, E, Pappas, PG, Thomas, C, Reingold, A, Rothrock, G, Hutwagner, LC, Schuchat, A, Brandt, ME, Pinner, RW, Farley, M, Bardsley, M, Siegel, B, Jackson, G, Lao, C, Otte, J, Harvey, C, Rimland, D, Gillespie, R, Pattni, B, Daily, P, Shihata, N & Durry, E 1999, 'Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons', Journal of Infectious Diseases, vol. 179, no. 2, pp. 449-454. https://doi.org/10.1086/314606

@article{a7d0dda6f8224f65a60204dbda1cc005,

title = "Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons",

abstract = "To determine the incidence of cryptococcosis and its risk factors among human immunodeficiency virus (HIV)-infected persons, population-based active surveillance was conducted in four US areas (population, 12.5 million) during 1992-1994, and a case-control study was done. Of 1083 cases, 931 (86%) occurred in HIV-infected persons. The annual incidence of cryptococcosis per 1000 among persons living with AIDS ranged from 17 (San Francisco, 1994) to 66 (Atlanta, 1992) and decreased significantly in these cities during 1992- 1994. Among non-HIV-infected persons, the annual incidence of cryptococcosis ranged from 0.2 to 0.9/100.000. Multivariate analysis of the case-control study (158 cases and 423 controls) revealed smoking and outdoor occupations to be significantly associated with an increased risk of cryptococcosis; receiving fluconazole within 3 months before enrollment was associated with a decreased risk for cryptococcosis. Further studies are needed to better describe persons with AIDS currently developing cryptococcosis in the era of highly active antiretroviral therapy.",

author = "Hajjeh, {Rana A.} and Conn, {Laura A.} and Stephens, {David S.} and Wendy Baughman and Richard Hamill and Edward Graviss and Pappas, {Peter G.} and Carolynn Thomas and Arthur Reingold and Gretchen Rothrock and Hutwagner, {Lori C.} and Anne Schuchat and Brandt, {Mary E.} and Pinner, {Robert W.} and Monica Farley and Molly Bardsley and Betsy Siegel and Georgia Jackson and Chris Lao and Jodie Otte and Christopher Harvey and David Rimland and Roger Gillespie and Bharat Pattni and Pam Daily and Nivin Shihata and Elias Durry",

year = "1999",

doi = "10.1086/314606",

language = "English (US)",

volume = "179",

pages = "449--454",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Cryptococcosis

T2 - Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons

AU - Hajjeh, Rana A.

AU - Conn, Laura A.

AU - Stephens, David S.

AU - Baughman, Wendy

AU - Hamill, Richard

AU - Graviss, Edward

AU - Pappas, Peter G.

AU - Thomas, Carolynn

AU - Reingold, Arthur

AU - Rothrock, Gretchen

AU - Hutwagner, Lori C.

AU - Schuchat, Anne

AU - Brandt, Mary E.

AU - Pinner, Robert W.

AU - Farley, Monica

AU - Bardsley, Molly

AU - Siegel, Betsy

AU - Jackson, Georgia

AU - Lao, Chris

AU - Otte, Jodie

AU - Harvey, Christopher

AU - Rimland, David

AU - Gillespie, Roger

AU - Pattni, Bharat

AU - Daily, Pam

AU - Shihata, Nivin

AU - Durry, Elias

PY - 1999

Y1 - 1999

N2 - To determine the incidence of cryptococcosis and its risk factors among human immunodeficiency virus (HIV)-infected persons, population-based active surveillance was conducted in four US areas (population, 12.5 million) during 1992-1994, and a case-control study was done. Of 1083 cases, 931 (86%) occurred in HIV-infected persons. The annual incidence of cryptococcosis per 1000 among persons living with AIDS ranged from 17 (San Francisco, 1994) to 66 (Atlanta, 1992) and decreased significantly in these cities during 1992- 1994. Among non-HIV-infected persons, the annual incidence of cryptococcosis ranged from 0.2 to 0.9/100.000. Multivariate analysis of the case-control study (158 cases and 423 controls) revealed smoking and outdoor occupations to be significantly associated with an increased risk of cryptococcosis; receiving fluconazole within 3 months before enrollment was associated with a decreased risk for cryptococcosis. Further studies are needed to better describe persons with AIDS currently developing cryptococcosis in the era of highly active antiretroviral therapy.

AB - To determine the incidence of cryptococcosis and its risk factors among human immunodeficiency virus (HIV)-infected persons, population-based active surveillance was conducted in four US areas (population, 12.5 million) during 1992-1994, and a case-control study was done. Of 1083 cases, 931 (86%) occurred in HIV-infected persons. The annual incidence of cryptococcosis per 1000 among persons living with AIDS ranged from 17 (San Francisco, 1994) to 66 (Atlanta, 1992) and decreased significantly in these cities during 1992- 1994. Among non-HIV-infected persons, the annual incidence of cryptococcosis ranged from 0.2 to 0.9/100.000. Multivariate analysis of the case-control study (158 cases and 423 controls) revealed smoking and outdoor occupations to be significantly associated with an increased risk of cryptococcosis; receiving fluconazole within 3 months before enrollment was associated with a decreased risk for cryptococcosis. Further studies are needed to better describe persons with AIDS currently developing cryptococcosis in the era of highly active antiretroviral therapy.

UR - http://www.scopus.com/inward/record.url?scp=0033021986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033021986&partnerID=8YFLogxK

U2 - 10.1086/314606

DO - 10.1086/314606

M3 - Article

C2 - 9878030

AN - SCOPUS:0033021986

SN - 0022-1899

VL - 179

SP - 449

EP - 454

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

IS - 2

ER -

Cryptococcosis: Population-based multistate active surveillance and risk factors in human immunodeficiency virus-infected persons

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this