TY - JOUR
T1 - Noninvasive brain stimulation in the treatment of functional urological and pelvic floor disorders
T2 - A scoping review
AU - Mazeaud, Charles
AU - Salazar, Betsy H.
AU - Khavari, Rose
N1 - Funding Information:
The authors thank Amy Taylor and the library department of Houston Methodist Hospital for methodological support and the use of Covidence software. The authors also thank Hamida Rajab for logistical and material support to provide the best working conditions in the Department of Urology. R. K. is partially supported by the National Institutes of Health NIDDK R03DK126994-01 award.
Funding Information:
The authors thank Amy Taylor and the library department of Houston Methodist Hospital for methodological support and the use of Covidence software. The authors also thank Hamida Rajab for logistical and material support to provide the best working conditions in the Department of Urology. R. K. is partially supported by the National Institutes of Health NIDDK R03DK126994‐01 award.
Publisher Copyright:
© 2023 Wiley Periodicals LLC.
PY - 2023/8
Y1 - 2023/8
N2 - INTRODUCTION: Functional pelvic floor disorders (PFD) such as bowel and bladder dysfunctions can be challenging to manage with our current therapeutic modalities. Recently, noninvasive brain stimulation has emerged as a novel strategy for noninvasive pelvic floor management. Here, we assessed the current state of research on this topic.METHODS: A scoping review was conducted with Pubmed, Web of Science, and Embase, in conjunction with clinicaltrials.gov, encompassing all manuscripts published without past time limit up until June 30, 2022.RESULTS: Of the 880 abstracts identified in a blind selection by two reviewers, 14 publications with an evidence level of 1 or 2 (Oxford scale) were eligible and included in this review. Review articles, case reports (<5 patients), letters, and protocol studies were excluded. PFDs were described as either pelvic pain or lower urinary tracts symptoms (LUTS) with repeated transcranial magnetic stimulation (rTMS) as the most common treatment modality. Despite heterogeneous therapeutic protocols, significant improvements were observed such as reduction in postvoid residual of urine, increased bladder capacity, improved voiding flow paraments, and decreased chronic pelvic, and bladder pain. No appreciable adverse effects were noted. However, low sample populations allowed only provisional conclusions.CONCLUSION: Noninvasive transcranial neurostimulation for LUTS and pelvic pain is emerging as an effective tool for clinicians to utilize in the future. Further investigation is needed to elucidate the full significance of the indicated outcomes.
AB - INTRODUCTION: Functional pelvic floor disorders (PFD) such as bowel and bladder dysfunctions can be challenging to manage with our current therapeutic modalities. Recently, noninvasive brain stimulation has emerged as a novel strategy for noninvasive pelvic floor management. Here, we assessed the current state of research on this topic.METHODS: A scoping review was conducted with Pubmed, Web of Science, and Embase, in conjunction with clinicaltrials.gov, encompassing all manuscripts published without past time limit up until June 30, 2022.RESULTS: Of the 880 abstracts identified in a blind selection by two reviewers, 14 publications with an evidence level of 1 or 2 (Oxford scale) were eligible and included in this review. Review articles, case reports (<5 patients), letters, and protocol studies were excluded. PFDs were described as either pelvic pain or lower urinary tracts symptoms (LUTS) with repeated transcranial magnetic stimulation (rTMS) as the most common treatment modality. Despite heterogeneous therapeutic protocols, significant improvements were observed such as reduction in postvoid residual of urine, increased bladder capacity, improved voiding flow paraments, and decreased chronic pelvic, and bladder pain. No appreciable adverse effects were noted. However, low sample populations allowed only provisional conclusions.CONCLUSION: Noninvasive transcranial neurostimulation for LUTS and pelvic pain is emerging as an effective tool for clinicians to utilize in the future. Further investigation is needed to elucidate the full significance of the indicated outcomes.
KW - pelvic floor disorder
KW - pelvic pain
KW - transcranial direct current stimulation
KW - transcranial magnetic stimulation
KW - urination disorder
KW - Brain
KW - Humans
KW - Pelvic Pain/therapy
KW - Pelvic Floor Disorders
KW - Transcranial Magnetic Stimulation/adverse effects
KW - Lower Urinary Tract Symptoms
KW - Urination/physiology
KW - Female
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U2 - 10.1002/nau.25205
DO - 10.1002/nau.25205
M3 - Review article
C2 - 37209294
AN - SCOPUS:85159688408
SN - 0733-2467
VL - 42
SP - 1318
EP - 1328
JO - Neurourology and Urodynamics
JF - Neurourology and Urodynamics
IS - 6
ER -