Abstract
Research using nonhuman primates (NHPs) has delivered fundamental knowledge about human diseases, and led to the development of valuable therapies for human patients. Nevertheless, the benefits of using NHPs in research must be carefully balanced against risks of harm to NHPs. In this chapter, we discuss the refinements in the care and use of NHPs in research. In particular, we focus on a number of important aspects regarding the training of both NHPs and care staff, the primate housing and husbandry, as well as the scientific practice and ethics. Although many of these aspects have been documented in national and international animal care guidelines, their recognition and application are not universal. Emphasizing these aspects is not only useful for the improvement of NHP welfare, but also provides a better basis for scientific research.
| Original language | English (US) |
|---|---|
| Title of host publication | Nonhuman Primate Models in Preclinical Research |
| Subtitle of host publication | Volume 1: Basics and Regulatory Principles |
| Publisher | Nova Science Publishers, Inc. |
| Pages | 1-16 |
| Number of pages | 16 |
| Volume | 1 |
| ISBN (Electronic) | 9781536199222 |
| State | Published - Jan 1 2021 |
Keywords
- Animal welfare
- Environmental and social enrichment
- Husbandry
- Nonhuman primate
- Positive reinforcement training
- Refinement
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)