TY - CHAP
T1 - The Macrophages and Intestinal Symbiosis
AU - Kloc, Malgorzata
AU - Uosef, Ahmed
AU - Elshawwaf, Mahmoud
AU - Abdelshafy, Ahmed Adel Abbas
AU - Elsaid, Kamal Mamdoh Kamal
AU - Kubiak, Jacek Z.
AU - Ghobrial, Rafik Mark
N1 - Funding Information:
Acknowledgments We are grateful for the support from The William Stamps Farish Fund and Polish Ministry of National Defense project “Kościuszko” no: 5508/2017/DA to JZ Kubiak. We acknowledge that some of the images used to make figures were from the Servier Medical ART: SMART, smart.servier.com.
Publisher Copyright:
© 2020, Springer Nature Switzerland AG.
PY - 2020
Y1 - 2020
N2 - The human intestinal tract is inhabited by trillions of microorganisms and houses the largest pool of macrophages in the human body. Being a part of the innate immune system, the macrophages, the professional phagocytes, vigorously respond to the microbial and dietary antigens present in the intestine. Because such a robust immune response poses the danger to the survival of the non-harmful and beneficial gut microbiota, the macrophages developed mechanisms of recognition and hyposensitivity toward the non-harmful/beneficial inhabitants of the gut. We will discuss the evolution and identity of some of these mechanisms in the following chapter.
AB - The human intestinal tract is inhabited by trillions of microorganisms and houses the largest pool of macrophages in the human body. Being a part of the innate immune system, the macrophages, the professional phagocytes, vigorously respond to the microbial and dietary antigens present in the intestine. Because such a robust immune response poses the danger to the survival of the non-harmful and beneficial gut microbiota, the macrophages developed mechanisms of recognition and hyposensitivity toward the non-harmful/beneficial inhabitants of the gut. We will discuss the evolution and identity of some of these mechanisms in the following chapter.
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U2 - 10.1007/978-3-030-51849-3_23
DO - 10.1007/978-3-030-51849-3_23
M3 - Chapter
C2 - 33263889
AN - SCOPUS:85097210257
T3 - Results and Problems in Cell Differentiation
SP - 605
EP - 616
BT - Results and Problems in Cell Differentiation
PB - Springer Science and Business Media Deutschland GmbH
ER -