Projects per year
Personal profile
Personal profile
Prior to completing her postdoctoral training in Canada, Dr. Kloc-Stepkowska was a tenured Associate Professor in the Department of Zoology at the University of Warsaw, Poland. She also served as a Research Associate in the Department of Biology at Carleton University in Ottawa, Canada. While completing her postdoctoral training, Dr. Kloc-Stepkowska earned the AHFMR Research Award from the University of Calgary and the MRC Biotechnology Training Award from Dalhousie University. She joined the University of Texas M.D. Anderson Cancer Center as a Research Scientist in the Department of Molecular Genetics in 1987, and became an Associate Professor in the Department of Biochemistry and Molecular Biology there in 2006. Dr. Kloc-Stepkowska joined the Houston Methodist Research Institute in 2008.
Research interests
Dr. Kloc-Stepkowska’s research focuses on investigations into the role of structural RNA in the organization of cellular cytoskeleton. She has numerous publications in the medical literature and her current studies are funded by the National Science Foundation. Dr. Kloc-Stepkowska also works closely with Dr. R. Mark Ghobrial on transplant immunomodulation studies using allochimeric molecules to improve transplant acceptance.
Education/Academic qualification
Biochemistry, Postdoctoral Fellowship, Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia
Biological Sciences, Postdoctoral Fellowship, Department of Biology, University of Calgary, Calgary, Alberta
Chemistry, Postdoctoral Fellowship, Department of Chemistry, Saint Mary's University, Halifax, Nova Scotia
Zoology, PhD, University of Warsaw
Biological Sciences, MS, University of Warsaw
Research Area Keywords
- Immunobiology & Inflammation
- Transplantation
Free-text keywords
- Immunology
- Transplant biology
- Structural RNA
- Cytoskeleton
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Collaborations and top research areas from the last five years
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A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation
Gaber, A. O., Ghobrial, R. M., Graviss, E. A., Hobeika, M. J., Kloc, M., Knight, R. J., Moore, L. W. & Yi, S.
1/13/20 → …
Project: Clinical Trial
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Real-world experience with Tecentriq + Avastin for the treatment of hepatocellular carcinoma (HCC) in the US
Abdelrahim, M., Connor, A. A., Dacha, S., Divatia, M. K., Esmail, A., Esnaola, N. F., Ghobrial, R. M., Graviss, E. A., Gupta, N., Heyne, K., Hobeika, M. J., Kloc, M., Kodali, S., Mobley, C. M., Moore, L. W., Noureddin, M., Rizk, E., Victor, III, D. W. & Xu, S.
Project: Clinical Trial
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Magnetic field-induced alteration of cytoskeleton to prevent rejection of transplanted organs
1/1/17 → 12/31/17
Project: Non Profit
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Germline and Somatic Cell Syncytia in Insects
Kloc, M., Tworzydło, W. & Szklarzewicz, T., 2024, In: Results and Problems in Cell Differentiation. 71, p. 47-63 17 p.Research output: Contribution to journal › Article › peer-review
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Invertebrate Immunity, Natural Transplantation Immunity, Somatic and Germ Cell Parasitism, and Transposon Defense
Kloc, M., Halasa, M., Kubiak, J. Z. & Ghobrial, R. M., Jan 2024, In: International journal of molecular sciences. 25, 2, 1072.Research output: Contribution to journal › Review article › peer-review
Open Access -
Osteocalcin protects islet identity in low-density lipoprotein receptor knockout mice on high-fat diet
Beamish, C. A., Lee, Y. K., Osama Gaber, A., Chanana, P., Graviss, E. A., Kloc, M., Waleed Gaber, M., Hsueh, W. A. & Sabek, O. M., Apr 2024, In: Journal of Endocrinology. 261, 1, e230352.Research output: Contribution to journal › Article › peer-review
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CDC6 as a Key Inhibitory Regulator of CDK1 Activation Dynamics and the Timing of Mitotic Entry and Progression
El Dika, M., Dudka, D., Kloc, M. & Kubiak, J. Z., Jun 14 2023, In: Biology. 12, 6, 855.Research output: Contribution to journal › Review article › peer-review
Open Access -
Comparative transcriptome profile of mouse macrophages treated with the RhoA/Rock pathway inhibitors Y27632, Fingolimod (Gilenya), and Rezurock (Belumosudil, SLx-2119)
Subuddhi, A., Uosef, A., Zou, D., Ubelaker, H. V., Ghobrial, R. M. & Kloc, M., May 1 2023, In: International Immunopharmacology. 118, p. 110017 110017.Research output: Contribution to journal › Article › peer-review
Prizes
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Distinguished Fellow of the Kosciuszko Foundation
Kloc, Malgorzata (Recipient), Jan 1 2014
Prize: Fellowship awarded competitively
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Foreign Member of Polish Academy of Sciences
Kloc, Malgorzata (Recipient), 2010
Prize: Other distinction
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Fulbright Senior Specialist Grant Award
Kloc, Malgorzata (Recipient), Jan 1 2003
Prize: Prize (including medals and awards)
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