Research output per year
Research output per year
- 24 results
Search results
-
2023
Intratumoral nanofluidic system enhanced tumor biodistribution of PD-L1 antibody in triple-negative breast cancer
Liu, H-C., Capuani, S., Badachhape, A. A., Di Trani, N., Davila Gonzalez, D., Vander Pol, R. S., Viswanath, D. I., Saunders, S., Hernandez, N., Ghaghada, K. B., Chen, S-H., Nance, E., Annapragada, A. V., Chua, C. Y. X. & Grattoni, A., Nov 2023, In: Bioengineering and Translational Medicine. 8, 6, p. e10594 e10594.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Engineered implantable vaccine platform for continuous antigen-specific immunomodulation
Viswanath, D. I., Liu, H. C., Capuani, S., Vander Pol, R. S., Saunders, S. Z., Chua, C. Y. X. & Grattoni, A., Feb 2022, In: Biomaterials. 281, p. 121374 121374.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats
Paez-Mayorga, J., Campa-Carranza, J. N., Capuani, S., Hernandez, N., Liu, H-C., Chua, C. Y. X., Pons-Faudoa, F. P., Malgir, G., Alvarez, B., Niles, J. A., Argueta, L. B., Shelton, K. A., Kezar, S., Nehete, P. N., Berman, D. M., Willman, M. A., Li, X. C., Ricordi, C., Nichols, J. E., Gaber, A. O., & 2 others, Dec 26 2022, In: Nature Communications. 13, 1, 7951.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Localization of drug biodistribution in a 3D-bioengineered subcutaneous neovascularized microenvironment
Capuani, S., Hernandez, N., Paez-Mayorga, J., Dogra, P., Wang, Z., Cristini, V., Chua, C. Y. X., Nichols, J. E. & Grattoni, A., Dec 2022, In: Materials Today Bio. 16, p. 100390 100390.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
2021
Carbon fiber reinforced polymers for implantable medical devices
Chua, C. Y. X., Liu, H. C., Di Trani, N., Susnjar, A., Ho, J., Scorrano, G., Rhudy, J., Sizovs, A., Lolli, G., Hernandez, N., Nucci, M. C., Cicalo, R., Ferrari, M. & Grattoni, A., Apr 2021, In: Biomaterials. 271, p. 120719 120719.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension
Di Trani, N., Liu, H. C., Qi, R., Viswanath, D. I., Liu, X., Chua, C. Y. X. & Grattoni, A., Oct 1 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 102417.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Potentiating Antitumor Efficacy Through Radiation and Sustained Intratumoral Delivery of Anti-CD40 and Anti-PDL1
Liu, H. C., Viswanath, D. I., Pesaresi, F., Xu, Y., Zhang, L., Di Trani, N., Paez-Mayorga, J., Hernandez, N., Wang, Y., Erm, D. R., Ho, J., Susnjar, A., Liu, X., Demaria, S., Chen, S. H., Teh, B. S., Butler, E. B., Xuan Chua, C. Y. & Grattoni, A., Jun 1 2021, In: International Journal of Radiation Oncology Biology Physics. 110, 2, p. 492-506 15 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Preventive Efficacy of a Tenofovir Alafenamide Fumarate Nanofluidic Implant in SHIV-Challenged Nonhuman Primates
Pons-Faudoa, F. P., Sizovs, A., Shelton, K. A., Momin, Z., Niles, J. A., Bushman, L. R., Xu, J., Chua, C. Y. X., Nichols, J. E., Demaria, S., Ittmann, M. M., Hawkins, T., Rooney, J. F., Marzinke, M. A., Kimata, J. T., Anderson, P. L., Nehete, P. N., Arduino, R. C., Ferrari, M., Sastry, K. J., & 1 others, Mar 2021, In: advanced therapeutics. 4, 3, p. 2000163 1 p., 2000163.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
2020
Cell Encapsulation: Enhanced In Vivo Vascularization of 3D-Printed Cell Encapsulation Device Using Platelet-Rich Plasma and Mesenchymal Stem Cells (Adv. Healthcare Mater. 19/2020)
Paez-Mayorga, J., Capuani, S., Farina, M., Lotito, M. L., Niles, J. A., Salazar, H. F., Rhudy, J., Esnaola, L., Chua, C. Y. X., Taraballi, F., Corradetti, B., Shelton, K. A., Nehete, P. N., Nichols, J. E. & Grattoni, A., 2020, In: Advanced Healthcare Materials. 9, 19Research output: Contribution to journal › Article › peer-review
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Counteracting Muscle Atrophy on Earth and in Space via Nanofluidics Delivery of Formoterol
Ballerini, A., Chua, C. Y. X., Rhudy, J., Susnjar, A., Di Trani, N., Jain, P. R., Laue, G., Lubicka, D., Shirazi-Fard, Y., Ferrari, M., Stodieck, L. S., Cadena, S. M. & Grattoni, A., Jul 1 2020, In: advanced therapeutics. 3, 7, 2000014.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Enhanced In Vivo Vascularization of 3D-Printed Cell Encapsulation Device Using Platelet-Rich Plasma and Mesenchymal Stem Cells
Paez-Mayorga, J., Capuani, S., Farina, M., Lotito, M. L., Niles, J. A., Salazar, H. F., Rhudy, J., Esnaola, L., Chua, C. Y. X., Taraballi, F., Corradetti, B., Shelton, K. A., Nehete, P. N., Nichols, J. E. & Grattoni, A., Oct 1 2020, In: Advanced Healthcare Materials. 9, 19, p. e2000670 2000670.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Intratumoral Nanofluidic System for Enhancing Tumor Biodistribution of Agonist CD40 Antibody
Chua, C. Y. X., Ho, J., Susnjar, A., Lolli, G., Di Trani, N., Pesaresi, F., Zhang, M., Nance, E. & Grattoni, A., Oct 1 2020, In: advanced therapeutics. 3, 10, 2000055.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation
Paez-Mayorga, J., Capuani, S., Hernandez, N., Farina, M., Chua, Y. X., Blanchard, R., Sizovs, A., Liu, H. C., Fraga, D. W., Niles, J. A., Salazar, H. F., Corradetti, B., Sikora, A. G., Kloc, M., Li, X. C., Gaber, A. O., Nichols, J. & Grattoni, A., Oct 2020, In: Biomaterials. 257, 120232.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Trans-urocanic acid enhances tenofovir alafenamide stability for long-acting HIV applications
Sizovs, A., Pons-Faudoa, F. P., Malgir, G., Shelton, K. A., Bushman, L. R., Chua, Y. X., Anderson, P. L., Nehete, P. N., Sastry, K. J. & Grattoni, A., Sep 25 2020, In: International Journal of Pharmaceutics. 587, 119623.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2019
2-Hydroxypropyl-β-cyclodextrin-enhanced pharmacokinetics of cabotegravir from a nanofluidic implant for HIV pre-exposure prophylaxis
Pons-Faudoa, F. P., Sizovs, A., Di Trani, N., Paez-Mayorga, J., Bruno, G., Rhudy, J., Manohar, M., Gwenden, K., Martini, C., Chua, C. Y. X., Varchi, G., Marzinke, M. A. & Grattoni, A., Jul 28 2019, In: Journal of Controlled Release. 306, p. 89-96 8 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Remotely controlled nanofluidic implantable platform for tunable drug delivery
Di Trani, N., Silvestri, A., Bruno, G., Geninatti, T., Chua, C. Y. X., Gilbert, A., Rizzo, G., Filgueira, C. S., Demarchi, D. & Grattoni, A., Jul 7 2019, In: Lab on a Chip. 19, 13, p. 2192-2204 13 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
2018
Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study
Filgueira, C. S., Bruno, G., Smith, Z. W., Chua, C. Y. X., Ballerini, A., Folci, M., Gilbert, A. L., Jain, P., Sastry, J. K., Nehete, P. N., Shelton, K. A., Hill, L. R., Ali, A., Youker, K. A. & Grattoni, A., Jun 1 2018, In: Biomedical Microdevices. 20, 2, 49.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Nanofluidic drug-eluting seed for sustained intratumoral immunotherapy in triple negative breast cancer
Chua, C. Y. X., Jain, P., Susnjar, A., Rhudy, J., Folci, M., Ballerini, A., Gilbert, A., Singh, S., Bruno, G., Filgueira, C. S., Yee, C., Butler, E. B. & Grattoni, A., Sep 10 2018, In: Journal of Controlled Release. 285, p. 23-34 12 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells
Farina, M., Chua, Y. X., Ballerini, A., Thekkedath, U., Alexander, J. F., Rhudy, J. R., Torchio, G., Fraga, D., Pathak, R. R., Villanueva, M., Shin, C. S., Niles, J. A., Sesana, R., Demarchi, D., Sikora, A. G., Acharya, G. S., Gaber, A. O., Nichols, J. & Grattoni, A., Sep 2018, In: Biomaterials. 177, p. 125-138 14 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
2016
Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies
Phillips, L. M., Zhou, X., Cogdell, D. E., Chua, C. Y., Huisinga, A., Hess, K. R., Fuller, G. N. & Zhang, W., Jul 1 2016, In: Journal of Pathology. 239, 3, p. 355-364 10 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
IGFBP2 activates the NF-κB pathway to drive epithelial-mesenchymal transition and invasive character in pancreatic ductal adenocarcinoma
Gao, S., Sun, Y., Zhang, X., Hu, L., Liu, Y., Chua, C. Y., Phillips, L. M., Ren, H., Fleming, J. B., Wang, H., Chiao, P. J., Hao, J. & Zhang, W., Nov 15 2016, In: Cancer research. 76, 22, p. 6543-6554 12 p.Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations -
IGFBP2 potentiates nuclear EGFR-STAT3 signaling
Chua, C. Y., Liu, Y., Granberg, K. J., Hu, L., Haapasalo, H., Annala, M. J., Cogdell, D. E., Verploegen, M., Moore, L. M., Fuller, G. N., Nykter, M., Cavenee, W. K. & Zhang, W., Feb 11 2016, In: Oncogene. 35, 6, p. 738-747 10 p.Research output: Contribution to journal › Article › peer-review
Open Access61 Scopus citations -
2012
An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma
Abraham, J., Chua, Y. X., Glover, J. M., Tyner, J. W., Loriaux, M. M., Kilcoyne, A., Giles, F. J., Nelon, L. D., Carew, J. S., Ouyang, Y., Michalek, J. E., Pal, R., Druker, B. J., Rubin, B. P. & Keller, C., Sep 28 2012, In: Biochemical and Biophysical Research Communications. 426, 3, p. 363-368 6 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network
Holmes, K. M., Annala, M., Chua, C. Y. X., Dunlap, S. M., Liu, Y., Hugen, N., Moore, L. M., Cogdell, D., Hu, L., Nykter, M., Hess, K., Fuller, G. N. & Zhang, W., Feb 28 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3475-3480 6 p.Research output: Contribution to journal › Article › peer-review
Open Access99 Scopus citations