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A Phase 3, Multicenter, Randomized, Controlled, Open-Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)
Faisal, H., Dhala, A., Masud, F. N., Mobley, C. M., Moore, L. W., Rizk, E. & Sanchez Leon, R.
2/3/23 → …
Project: Clinical Trial
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A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in Participants With High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease in Breast
Mai, H. P., Chang, J. C., Niravath, P. A. & Sun, K.
Project: Clinical Trial
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A Phase 3 Open-Label, Randomized Study of Fixed Duration Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab Versus Venetoclax and Rituximab in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (BRUIN CLL-322)
Shah, S., Ganguly, S., Mai, H. P., Petkova, J., Pingali, S. R. & Rice, L.
9/21/22 → …
Project: Clinical Trial
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A Phase I, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Activity of TRL1068 in Subjects with Prosthetic Joint Infection of the Knee or Hip and Undergoing Primary Two-Stage Exchange Arthroplasty.
Incavo, S. J. & Salas-Vargas, A. V.
Project: Clinical Trial
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A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio
Bernicker, E. H., Darcourt, J. & Singh, M.
6/11/13 → 6/10/38
Project: Non Profit
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A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients
Ghobrial, R. M., Abdelrahim, M. & Kodali, S.
4/1/21 → 3/31/26
Project: Federal Funding Agencies
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A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)
5/23/22 → 5/22/26
Project: Non Profit
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A Phase II Clinical tRial of neoADjuVant sAsanlimab and stereotaCtiC body radIatioN thErapy as an in situ vaccine for cisplatin-ineligible Muscle Invasive Bladder Cancer (RAD VACCINE MIBC)
Satkunasivam, R., Butler, E. B., Chen, S., Esnaola, N. F., Farach, A. M., Teh, B. S. & Zhang, J.
1/20/22 → …
Project: Clinical Trial
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A Phase III, adjudicator-blinded, randomised study to evaluate the efficacy and safety of treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with invasive fungal disease (IFD) caused by Aspergillus species
Grimes, K. A., Lin, J., Malik, A. I. & Nigo, M.
11/16/23 → …
Project: Clinical Trial
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A Phase III, Multicenter, Open-Label, Extension Clinical Trial to Demonstrate the Effectiveness and Safety of Liposomal Cyclosporine A (L-CsA) Inhalation Solution Delivered via the PARI Investigational eFlow® Device plus Standard of Care in the Treatment of Bronchiolitis Obliterans Syndrome in Patients post Single or Double Lung Transplantation (BT-L-CsA-303-FU (BOSTON-3))
Huang, H. J., Botros, M., Goodarzi, A., Yau, S. W. & Youssef, J. G.
5/27/20 → …
Project: Clinical Trial
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A phase III, multicenter, randomized, study of atezolizumab/placebo administered in combination with paclitaxel, carboplatin, and bevacizumab to patients with newly-diagnosed stage III or stage IV ovarian, fallopian tube, or primary peritoneal cancer
Kamat, A. A., Alaniz, A., Bernicker, E. H., Darcourt, J., Heyne, K., Singh, M., Suri, A. & Zaid, T.
3/13/18 → 3/12/43
Project: Non Profit
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A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)
6/10/22 → 5/31/27
Project: Federal Funding Agencies
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A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation
7/10/18 → 12/31/22
Project: Federal Funding Agencies
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A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation
3/26/20 → 3/25/45
Project: Non Profit
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A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease
2/13/19 → …
Project: Clinical Trial
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APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
Ibrahim, H. N.
6/1/19 → 5/31/20
Project: Federal Funding Agencies
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A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy
Templeton, S., Arentz, C., Chang, J. C., Darcourt, J., Dubrovsky, E., Haque, W. M., Heyne, K., Morgan, P. B., Niravath, P. A. & Singh, M.
Project: Clinical Trial
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A Randomized, Double-blind, Phase 3 Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer (ENGOT-0V44 The FIRST)
Suri, A., Alaniz, A., Singh, M. & Zaid, T.
Project: Clinical Trial
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A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo
Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Heyne, K. & Singh, M.
Project: Clinical Trial
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A Randomized, Double-blind, Phase III Study, Comparing NIS793 in Combination With Gemcitabine and Nab-paclitaxel Versus (vs.) Placebo Combined With Gemcitabine and Nab-paclitaxel for First Line Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Abdelrahim, M., Heyne, K. & Singh, M.
Project: Clinical Trial
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A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer
Chang, J. C., Darcourt, J., Geyer, C. E. & Niravath, P. A.
Project: Clinical Trial