Accepting PhD Students

PhD projects

1) Molecular mechanisms for the regulation of autophagy;
2) Molecular regulation of memory T cells and memory B cells against infections.

Calculated based on number of publications stored in Pure and citations from Scopus
1994 …2023

Research activity per year

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  • 2023

    A modeling-based approach to optimize COVID-19 vaccine dosing schedules for improved protection

    Dogra, P., Schiavone, C., Wang, Z., Ruiz-Ramírez, J., Caserta, S., Staquicini, D. I., Markosian, C., Wang, J., Sostman, H. D., Pasqualini, R., Arap, W. & Cristini, V., Jul 10 2023, In: JCI insight. 8, 13, e169860.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Targeting HIV-1 reservoirs in T cell subsets

    Li, M., Budai, M. M., Chen, M. & Wang, J., Jan 20 2023, In: Frontiers in immunology. 14, p. 1087923 1087923.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • 2022

    Mathematical modeling identifies optimal dosing schedules for COVID-19 vaccines to minimize breakthrough infections

    Dogra, P., Schiavone, C., Wang, Z., Ramírez, J. R., Caserta, S., Staquicini, D. I., Markosian, C., Wang, J., Sostman, H. D., Pasqualini, R., Arap, W. & Cristini, V., Sep 17 2022, In: medRxiv.

    Research output: Contribution to journalArticle

  • Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling

    Chen, M., Wang, L., Li, M., Budai, M. M. & Wang, J., Oct 2022, In: Cells. 11, 19, p. 1 22 p., 3053.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy

    Kodali, S., Li, M., Budai, M. M., Chen, M. & Wang, J., Mar 1 2022, In: Journal of Immunology. 208, 5, p. 1085-1098 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Regulation of Mitochondrial Homeostasis and Metabolic Programming in Memory B cells by Mitophagy

    Budai, M. M., Li, M., Kodali, S., Chen, M. & Wang, J., Apr 20 2022, In: Autophagy Reports. 1, 1, p. 165-169 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2021

    A recombinant bovine adenoviral mucosal vaccine expressing mycobacterial antigen-85B generates robust protection against tuberculosis in mice

    Khan, A., Sayedahmed, E. E., Singh, V. K., Mishra, A., Dorta-Estremera, S., Nookala, S., Canaday, D. H., Chen, M., Wang, J., Sastry, K. J., Mittal, S. K. & Jagannath, C., Aug 17 2021, In: Cell Reports Medicine. 2, 8, p. 100372 100372.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Dependence on Autophagy for Autoreactive Memory B Cells in the Development of Pristane-Induced Lupus

    Jang, A., Sharp, R., Wang, J. M., Feng, Y., Wang, J. & Chen, M., Jul 16 2021, In: Frontiers in immunology. 12, p. 701066 14 p., 701066.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • 2020

    Author Correction: Clearance of HIV infection by selective elimination of host cells capable of producing HIV

    Li, M., Liu, W., Bauch, T., Graviss, E. A., Arduino, R. C., Kimata, J. T., Chen, M. & Wang, J., Dec 2 2020, In: Nature Communications. 11, 1, p. 6281 6281.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Clearance of HIV infection by selective elimination of host cells capable of producing HIV

    Li, M., Liu, W., Bauch, T., Graviss, E. A., Arduino, R. C., Kimata, J. T., Chen, M. & Wang, J., Aug 13 2020, In: Nature Communications. 11, 1, p. 4051 4051.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    18 Scopus citations
  • Maintenance of Germinal Center B cells by Caspase-9 through Promotion of Apoptosis and Inhibition of Necroptosis.

    Zhang, J., Kodali, S., Chen, M. & Wang, J., Jul 1 2020, In: Journal of Immunology. 205, 1, p. 113-120 8 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • 2019

    An autophagy-inducing and TLR-2 activating BCG vaccine induces a robust protection against tuberculosis in mice

    Khan, A., Bakhru, P., Saikolappan, S., Das, K., Soudani, E., Singh, C. R., Estrella, J. L., Zhang, D., Pasare, C., Ma, Y., Sun, J., Wang, J., Hunter, R. L., Tony Eissa, N., Dhandayuthapani, S. & Jagannath, C., Dec 1 2019, In: npj Vaccines. 4, 1, p. 34 34.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • NIX-Mediated Mitophagy Promotes Effector Memory Formation in Antigen-Specific CD8+ T Cells

    Gupta, S. S., Sharp, R., Hofferek, C., Kuai, L., Dorn, G. W., Wang, J. & Chen, M., Nov 12 2019, In: Cell Reports. 29, 7, p. 1862-1877.e7

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication

    Zhang, J., Ruan, T., Sheng, T., Wang, J., Sun, J., Wang, J., Prinz, R. A., Peng, D., Liu, X. & Xu, X., Jan 2 2019, In: Virology. 526, p. 1-12 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    33 Scopus citations
  • 2018

    Atg5 Supports R. australis Infection in Macrophages in vitro and in vivo

    Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Oct 8 2018, In: Infection and Immunity. p. IAI.00651-18

    Research output: Contribution to journalArticlepeer-review

    27 Scopus citations
  • 2017

    Ablation of Transcription Factor IRF4 Promotes Transplant Acceptance by Driving Allogenic CD4+ T Cell Dysfunction

    Wu, J., Zhang, H., Shi, X., Xiao, X., Fan, Y., Minze, L. J., Wang, J., Ghobrial, R. M., Xia, J., Sciammas, R., Li, X. C. & Chen, W., Dec 4 2017, (E-pub ahead of print) In: Immunity.

    Research output: Contribution to journalArticlepeer-review

    74 Scopus citations
  • Regulation of B cell fate, survival, and function by mitochondria and autophagy

    Sandoval, H., Kodali, S. & Wang, J., Nov 23 2017, (E-pub ahead of print) In: Mitochondrion.

    Research output: Contribution to journalArticlepeer-review

    54 Scopus citations
  • Supramolecular Peptide Nanofibers Engage Mechanisms of Autophagy in Antigen-Presenting Cells

    Rudra, J. S., Khan, A., Clover, T. M., Endsley, J. J., Zloza, A., Wang, J. & Jagannath, C., 2017, In: ACS Omega. 2, 12, p. 9136-9143 8 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • TRIM29 promotes DNA virus infections by inhibiting innate immune response

    Xing, J., Zhang, A., Zhang, H., Wang, J., Li, X. C., Zeng, M-S. & Zhang, Z., Oct 16 2017, In: Nature Communications. 8, 1, 945.

    Research output: Contribution to journalArticlepeer-review

    141 Scopus citations
  • 2016

    Challenges and strategies for the eradication of the HIV reservoir

    Kimata, J. T., Rice, A. P. & Wang, J., Oct 2016, In: Current Opinion in Immunology. 42, p. 65-70 6 p.

    Research output: Contribution to journalArticle

    50 Scopus citations
  • 2015

    Requirement for autophagy in the long-term persistence but not initial formation of memory B cells

    Chen, M., Kodali, S., Jang, A., Kuai, L. & Wang, J., Mar 15 2015, In: Journal of Immunology. 194, 6, p. 2607-15 9 p.

    Research output: Contribution to journalArticlepeer-review

    52 Scopus citations
  • 2014

    Essential role for autophagy in the maintenance of immunological memory against influenza infection.

    Chen, M., Hong, M. J., Sun, H., Wang, L., Shi, X., Gilbert, B. E., Corry, D. B., Kheradmand, F. & Wang, J., Apr 20 2014, In: Nature Medicine. 20, 5, p. 503-510 8 p.

    Research output: Contribution to journalArticlepeer-review

    161 Scopus citations
  • 2013

    Analyses of programmed cell death in dendritic cells

    Chen, M., Huang, L. & Wang, J., 2013, In: Methods in molecular biology (Clifton, N.J.). 979, p. 51-63 13 p.

    Research output: Contribution to journalArticle

  • Cleavage of anti-apoptotic Bcl-2 family members after TCR stimulation contributes to the decision between T cell activation and apoptosis

    Guerrero, A. D., Welschhans, R. L., Chen, M. & Wang, J., Jan 1 2013, In: Journal of Immunology. 190, 1, p. 168-73 6 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • 2012

    Critical role for perforin and Fas-dependent killing of dendritic cells in the control of inflammation

    Chen, M., Felix, K. & Wang, J., Jan 5 2012, In: Blood. 119, 1, p. 127-36 10 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J., & 1,249 othersAleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W. L., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D. S., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B. A., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F. F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. 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K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 1 2012, In: Autophagy. 8, 4, p. 445-544 100 p.

    Research output: Contribution to journalArticlepeer-review

    2892 Scopus citations
  • Promotion of Caspase Activation by Caspase-9-mediated Feedback Amplification of Mitochondrial Damage

    Guerrero, A. D., Schmitz, I., Chen, M. & Wang, J., Aug 9 2012, In: Journal of clinical & cellular immunology. 3, 3

    Research output: Contribution to journalArticlepeer-review

  • 2011

    Immune regulation through mitochondrion-dependent dendritic cell death induced by T regulatory cells

    Chen, M., Felix, K. & Wang, J., Dec 1 2011, In: Journal of Immunology. 187, 11, p. 5684-92 9 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • 2010

    Programmed cell death of dendritic cells in immune regulation

    Chen, M. & Wang, J., Jul 2010, In: Immunological Reviews. 236, p. 11-27 17 p.

    Research output: Contribution to journalArticle

    50 Scopus citations
  • 2008

    Delineation of the caspase-9 signaling cascade

    Guerrero, A. D., Chen, M. & Wang, J., Jan 2008, In: Apoptosis. 13, 1, p. 177-86 10 p.

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Essential role for Nix in autophagic maturation of erythroid cells

    Sandoval, H., Thiagarajan, P., Dasgupta, S. K., Schumacher, A., Prchal, J. T., Chen, M. & Wang, J., Jul 10 2008, In: Nature. 454, 7201, p. 232-5 4 p.

    Research output: Contribution to journalArticlepeer-review

    946 Scopus citations
  • Selective mitochondrial autophagy during erythroid maturation

    Chen, M., Sandoval, H. & Wang, J., Oct 2008, In: Autophagy. 4, 7, p. 926-8 3 p.

    Research output: Contribution to journalArticle

    40 Scopus citations
  • 2007

    Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members

    Chen, M., Guerrero, A. D., Huang, L., Shabier, Z., Pan, M., Tan, T-H. & Wang, J., Nov 16 2007, In: The Journal of biological chemistry. 282, 46, p. 33888-95 8 p.

    Research output: Contribution to journalArticlepeer-review

    98 Scopus citations
  • Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity

    Chen, M., Huang, L. & Wang, J., May 15 2007, In: Blood. 109, 10, p. 4360-7 8 p.

    Research output: Contribution to journalArticlepeer-review

    95 Scopus citations
  • Regulation of the lifespan in dendritic cell subsets

    Chen, M., Huang, L., Shabier, Z. & Wang, J., Apr 2007, In: Molecular Immunology. 44, 10, p. 2558-65 8 p.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations
  • 2006

    Dendritic cell apoptosis in the maintenance of immune tolerance

    Chen, M., Wang, Y-H., Wang, Y., Huang, L., Sandoval, H., Liu, Y-J. & Wang, J., Feb 24 2006, In: Science (New York, N.Y.). 311, 5764, p. 1160-4 5 p.

    Research output: Contribution to journalArticlepeer-review

    285 Scopus citations
  • 2002

    Activation of initiator caspases through a stable dimeric intermediate

    Chen, M., Orozco, A., Spencer, D. M. & Wang, J., Dec 27 2002, In: The Journal of biological chemistry. 277, 52, p. 50761-7 7 p.

    Research output: Contribution to journalArticlepeer-review

    55 Scopus citations
  • Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

    Chun, H. J., Zheng, L., Ahmad, M., Wang, J., Speirs, C. K., Siegel, R. M., Dale, J. K., Puck, J., Davis, J., Hall, C. G., Skoda-Smith, S., Atkinson, T. P., Straus, S. E. & Lenardo, M. J., Sep 26 2002, In: Nature. 419, 6905, p. 395-399 5 p.

    Research output: Contribution to journalArticlepeer-review

    596 Scopus citations
  • 2001

    Caspase-10 is an initiator caspase in death receptor signaling

    Wang, J., Chun, H. J., Wong, W., Spencer, D. M. & Lenardo, M. J., Nov 20 2001, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 24, p. 13884-13888 5 p.

    Research output: Contribution to journalArticlepeer-review

    321 Scopus citations
  • The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

    Straus, S. E., Jaffe, E. S., Puck, J. M., Dale, J. K., Elkon, K. B., Rösen-Wolff, A., Peters, A. M. J., Sneller, M. C., Hallahan, C. W., Wang, J., Fischer, R. E., Jackson, C. M., Lin, A. Y., Bäumler, C., Siegert, E., Marx, A., Vaishnaw, A. K., Grodzicky, T., Fleisher, T. A. & Lenardo, M. J., Jul 1 2001, In: Blood. 98, 1, p. 194-200 7 p.

    Research output: Contribution to journalArticlepeer-review

    376 Scopus citations
  • 2000

    Inhibition of Fas-mediated apoptosis by the B cell antigen receptor through c-FLIP

    Wang, J., Lobito, A. A., Shen, F., Hornung, F., Winoto, A. & Lenardo, M. J., 2000, In: European Journal of Immunology. 30, 1, p. 155-163 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    124 Scopus citations
  • 1999

    Autoimmune lymphoproliferative syndrome with defective Fas: Genotype influences penetrance

    Jackson, C. E., Fischer, R. E., Hsu, A. P., Anderson, S. M., Choi, Y., Wang, J., Dale, J. K., Fleisher, T. A., Middelton, L. A., Sneller, M. C., Lenardo, M. J., Straus, S. E. & Puck, J. M., 1999, In: American Journal of Human Genetics. 64, 4, p. 1002-1014 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    190 Scopus citations
  • Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia

    Martin, D. A., Zheng, L., Siegel, R. M., Huang, B., Fisher, G. H., Wang, J., Jackson, C. E., Puck, J. M., Dale, J., Straus, S. E., Peter, M. E., Krammer, P. H., Fesik, S. & Lenardo, M. J., Apr 13 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 8, p. 4552-4557 6 p.

    Research output: Contribution to journalArticlepeer-review

    159 Scopus citations
  • Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

    Wang, J., Zheng, L., Lobito, A., Chan, F. K. M., Dale, J., Sneller, M., Yao, X., Puck, J. M., Straus, S. E. & Lenardo, M. J., Jul 9 1999, In: Cell. 98, 1, p. 47-58 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    529 Scopus citations
  • 1997

    Clinical, immunologic, and genetic features of an autoimmune lymphoproliferative syndrome associated with abnormal lymphocyte apoptosis

    Sneller, M. C., Wang, J., Dale, J. K., Strober, W., Middelton, L. A., Choi, Y., Fleisher, T. A., Lim, M. S., Jaffe, E. S., Puck, J. M., Lenardo, M. J. & Straus, S. E., Feb 15 1997, In: Blood. 89, 4, p. 1341-1348 8 p.

    Research output: Contribution to journalArticlepeer-review

    339 Scopus citations
  • Essential lymphocyte function associated 1 (LFA-1): Intercellular adhesion molecule interactions for T cell-mediated B cell apoptosis by Fas/APO-1/CD95

    Wang, J. & Lenardo, M. J., Oct 6 1997, In: Journal of Experimental Medicine. 186, 7, p. 1171-1176 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    43 Scopus citations
  • Molecules involved in cell death and peripheral tolerance

    Wang, J. & Lenardo, M. J., Jan 1 1997, In: Current Opinion in Immunology. 9, 6, p. 818-825 8 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Regulation of cytotoxic T cell functions by a GPI-anchored ecto-ADP- ribosyltransferase

    Wang, J., Nemoto, E. & Dennert, G., 1997, In: Advances in experimental medicine and biology. 419, p. 191-201 11 p.

    Research output: Contribution to journalArticlepeer-review

    9 Scopus citations
  • 1996

    Regulation of CTL by ecto-nictinamide adenine dinucleotide (NAD) involves ADP-ribosylation of a p56lck-associated protein.

    Wang, J., Nemoto, E. & Dennert, G., Apr 15 1996, In: Journal of immunology (Baltimore, Md. : 1950). 156, 8, p. 2819-2827 9 p.

    Research output: Contribution to journalArticlepeer-review

    58 Scopus citations